AIMC Topic: Micromanipulation

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Robotic Immobilization of Motile Sperm for Clinical Intracytoplasmic Sperm Injection.

IEEE transactions on bio-medical engineering
OBJECTIVE: In clinical intracytoplasmic sperm injection (ICSI), a motile sperm must be immobilized before insertion into an oocyte. This paper aims to develop a robotic system for automated tracking, orientation control, and immobilization of motile ...

Towards Robot-Assisted Retinal Vein Cannulation: A Motorized Force-Sensing Microneedle Integrated with a Handheld Micromanipulator .

Sensors (Basel, Switzerland)
Retinal vein cannulation is a technically demanding surgical procedure where therapeutic agents are injected into the retinal veins to treat occlusions. The clinical feasibility of this approach has been largely limited by the technical challenges as...

Cooperative Micromanipulation Using the Independent Actuation of Fifty Microrobots in Parallel.

Scientific reports
Micromanipulation for applications in areas such as tissue engineering can require mesoscale structures to be assembled with microscale resolution. One method for achieving such manipulation is the parallel actuation of many microrobots in parallel. ...

Switched Fuzzy-PD Control of Contact Forces in Robotic Microbiomanipulation.

IEEE transactions on bio-medical engineering
Force sensing and control are of paramount importance in robotic micromanipulation. A contact force regulator capable of accurately applying mechanical stimuli to a live Drosophila larva could greatly facilitate mechanobiology research on Drosophila ...

Autofocusing and Polar Body Detection in Automated Cell Manipulation.

IEEE transactions on bio-medical engineering
Autofocusing and feature detection are two essential processes for performing automated biological cell manipulation tasks. In this paper, we have introduced a technique capable of focusing on a holding pipette and a mammalian cell under a bright-fie...

Development of a control algorithm for the ultrasound scanning robot (NCCUSR) using ultrasound image and force feedback.

The international journal of medical robotics + computer assisted surgery : MRCAS
BACKGROUND: Clinicians who frequently perform ultrasound scanning procedures often suffer from musculoskeletal disorders, arthritis, and myalgias. To minimize their occurrence and to assist clinicians, ultrasound scanning robots have been developed w...

Robotic adherent cell injection for characterizing cell-cell communication.

IEEE transactions on bio-medical engineering
Compared to robotic injection of suspended cells (e.g., embryos and oocytes), fewer attempts were made to automate the injection of adherent cells (e.g., cancer cells and cardiomyocytes) due to their smaller size, highly irregular morphology, small t...

Translational and rotational manipulation of filamentous cells using optically driven microrobots.

Optics express
Optical cell manipulation has become increasingly valuable in cell-based assays. In this paper, we demonstrate the translational and rotational manipulation of filamentous cells using multiple cooperative microrobots automatically driven by holograph...

Steerable Robot-assisted Micromanipulation in the Middle Ear: Preliminary Feasibility Evaluation.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
HYPOTHESIS: The use of a robotic manipulator with a dexterously orientable gripper will expand the ability of middle ear surgeons to perform precise tasks and access otherwise challenging anatomic regions.

Programmable assembly of heterogeneous microparts by an untethered mobile capillary microgripper.

Lab on a chip
At the sub-millimeter scale, capillary forces enable robust and reversible adhesion between biological organisms and varied substrates. Current human-engineered mobile untethered micromanipulation systems rely on forces which scale poorly or utilize ...