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Natural Language Processing

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Automated analysis of spoken language differentiates multiple system atrophy from Parkinson's disease.

Journal of neurology
BACKGROUND AND OBJECTIVES: Patients with synucleinopathies such as multiple system atrophy (MSA) and Parkinson's disease (PD) frequently display speech and language abnormalities. We explore the diagnostic potential of automated linguistic analysis o...

BiomedRAG: A retrieval augmented large language model for biomedicine.

Journal of biomedical informatics
Retrieval-augmented generation (RAG) involves a solution by retrieving knowledge from an established database to enhance the performance of large language models (LLM). , these models retrieve information at the sentence or paragraph level, potential...

Natural language processing to identify suicidal ideation and anhedonia in major depressive disorder.

BMC medical informatics and decision making
BACKGROUND: Anhedonia and suicidal ideation are symptoms of major depressive disorder (MDD) that are not regularly captured in structured scales but may be captured in unstructured clinical notes. Natural language processing (NLP) techniques may be u...

Hierarchical graph-based integration network for propaganda detection in textual news articles on social media.

Scientific reports
During the Covid-19 pandemic, the widespread use of social media platforms has facilitated the dissemination of information, fake news, and propaganda, serving as a vital source of self-reported symptoms related to Covid-19. Existing graph-based mode...

Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique.

Computers in biology and medicine
Protein succinylation, a post-translational modification wherein a succinyl group (-CO-CH₂-CH₂-CO-) attaches to lysine residues, plays a critical regulatory role in cellular processes. Dysregulated succinylation has been implicated in the onset and p...

The role of chromatin state in intron retention: A case study in leveraging large scale deep learning models.

PLoS computational biology
Complex deep learning models trained on very large datasets have become key enabling tools for current research in natural language processing and computer vision. By providing pre-trained models that can be fine-tuned for specific applications, they...

Enhancing semantical text understanding with fine-tuned large language models: A case study on Quora Question Pair duplicate identification.

PloS one
Semantical text understanding holds significant importance in natural language processing (NLP). Numerous datasets, such as Quora Question Pairs (QQP), have been devised for this purpose. In our previous study, we developed a Siamese Convolutional Ne...

The advantages of lexicon-based sentiment analysis in an age of machine learning.

PloS one
Assessing whether texts are positive or negative-sentiment analysis-has wide-ranging applications across many disciplines. Automated approaches make it possible to code near unlimited quantities of texts rapidly, replicably, and with high accuracy. C...

Harnessing NLP to investigate biomarker interactions and CVD risks in elderly chronic kidney disease patients.

SLAS technology
Chronic kidney disease (CKD) significantly increases the risk of CVD diseases, particularly among elderly patients. Understanding the interaction between several biomarkers and cardiovascular (CVD) risks is crucial for improving patient outcomes and ...

Leveraging Natural Language Processing and Machine Learning Methods for Adverse Drug Event Detection in Electronic Health/Medical Records: A Scoping Review.

Drug safety
BACKGROUND: Natural language processing (NLP) and machine learning (ML) techniques may help harness unstructured free-text electronic health record (EHR) data to detect adverse drug events (ADEs) and thus improve pharmacovigilance. However, evidence ...