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A vision-language foundation model for precision oncology.

Nature
Clinical decision-making is driven by multimodal data, including clinical notes and pathological characteristics. Artificial intelligence approaches that can effectively integrate multimodal data hold significant promise in advancing clinical care. H...

Utilizing Feature Selection Techniques for AI-Driven Tumor Subtype Classification: Enhancing Precision in Cancer Diagnostics.

Biomolecules
Cancer's heterogeneity presents significant challenges in accurate diagnosis and effective treatment, including the complexity of identifying tumor subtypes and their diverse biological behaviors. This review examines how feature selection techniques...

Artificial Intelligence, Machine Learning and Big Data in Radiation Oncology.

Hematology/oncology clinics of North America
This review explores the applications of artificial intelligence and machine learning (AI/ML) in radiation oncology, focusing on computer vision (CV) and natural language processing (NLP) techniques. We examined CV-based AI/ML in digital pathology an...

MiRS-HF: A Novel Deep Learning Predictor for Cancer Classification and miRNA Expression Patterns.

IEEE journal of biomedical and health informatics
Cancer classification and biomarker identification are crucial for guiding personalized treatment. To make effective use of miRNA associations and expression data, we have developed a deep learning model for cancer classification and biomarker identi...

Partial-Label Contrastive Representation Learning for Fine-Grained Biomarkers Prediction From Histopathology Whole Slide Images.

IEEE journal of biomedical and health informatics
In the domain of histopathology analysis, existing representation learning methods for biomarkers prediction from whole slide images (WSIs) face challenges due to the complexity of tissue subtypes and label noise problems. This paper proposed a novel...

Deep Drug Synergy Prediction Network Using Modified Triangular Mutation-Based Differential Evolution.

IEEE journal of biomedical and health informatics
Drug combination therapy is crucial in cancer treatment, but accurately predicting drug synergy remains a challenge due to the complexity of drug combinations. Machine learning and deep learning models have shown promise in drug combination predictio...

Understanding the role of the gut microbiome in solid tumor responses to immune checkpoint inhibitors for personalized therapeutic strategies: a review.

Frontiers in immunology
Immunotherapy, especially immune checkpoint inhibitor (ICI) therapy, has yielded remarkable outcomes for some patients with solid cancers, but others do not respond to these treatments. Recent research has identified the gut microbiota as a key modul...

Intelligence analysis of drug nanoparticles delivery efficiency to cancer tumor sites using machine learning models.

Scientific reports
This study focuses on the use of machine learning (ML) models to predict the biodistribution of nanoparticles in various organs, using a dataset derived from research on nanoparticle behavior for cancer treatment. The dataset includes both categorica...

The global trends and distribution in tumor-infiltrating lymphocytes over the past 49 years: bibliometric and visualized analysis.

Frontiers in immunology
BACKGROUND: The body of research on tumor-infiltrating lymphocytes (TILs) is expanding rapidly; yet, a comprehensive analysis of related publications has been notably absent.

Self-interactive learning: Fusion and evolution of multi-scale histomorphology features for molecular traits prediction in computational pathology.

Medical image analysis
Predicting disease-related molecular traits from histomorphology brings great opportunities for precision medicine. Despite the rich information present in histopathological images, extracting fine-grained molecular features from standard whole slide...