Histopathology with hematoxylin and eosin (H&E) staining is routinely employed for clinical diagnoses. Single-cell analysis of histopathology provides a powerful tool for understanding the intricate cellular interactions underlying disease progressio...
International journal of pharmaceutics
Jul 5, 2025
Lab-on-a-chip (LoC) technologies have emerged as transformative tools in cancer research, particularly in evaluating drug resistance, which remains a significant barrier to effective treatment. These miniaturized platforms allow for the integration o...
BMC medical informatics and decision making
Jul 4, 2025
BACKGROUND: The incidence of intensive care unit (ICU) admissions and the corresponding mortality rates among cancer patients are both high. However, the existing scoring systems all lack specificity. This research seeks to establish and validate a p...
Although significant advances have been made in the early detection of many cancers, challenges remain in the early diagnosis of rare cancers, including Wilms tumor, Clear Cell Sarcoma of the Kidney, Neuroblastoma, Osteosarcoma, and Acute Myeloid Leu...
Effective clinical management of patients with cancer requires highly accurate diagnosis, precise therapy selection, and highly sensitive monitoring of disease burden. Caris Assure is a multifunctional blood-based assay that couples whole exome and w...
In the field of cancer therapy, the diversity and heterogeneity of cancer genomes in clinical patients complicate and challenge the effective use of non-targeted drugs, as these drugs often fail to address specific genetic events. Recent advancements...
Despite advances in precision oncology, developing effective cancer therapeutics remains a significant challenge due to tumor heterogeneity and the limited availability of well-defined drug targets. Recent progress in generative artificial intelligen...
Angewandte Chemie (International ed. in English)
Jun 30, 2025
Specific subpopulations of extracellular vesicles (EVs) hold significant clinical potential for biomarker discovery, disease diagnosis, and therapeutic agents. However, this field remains underutilized due to the lack of straightforward and versatile...
PURPOSE: This study aimed to investigate whether changes in step count, measured using patients' own smartphones, could predict a clinical adverse event in the upcoming week in patients undergoing systemic anticancer treatments using machine learning...
Noninvasive odor sensing is important in environmental monitoring and medical diagnosis. The two-dimensional material MXene is widely used due to its unique sensing properties but has limitations in specifically recognizing a certain gas. This study ...
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