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An in-depth examination of the fuzzy fractional cancer tumor model and its numerical solution by implicit finite difference method.

PloS one
The cancer tumor model serves a s a crucial instrument for understanding the behavior of different cancer tumors. Researchers have employed fractional differential equations to describe these models. In the context of time fractional cancer tumor mod...

Transferable deep learning with coati optimization algorithm based mitotic nuclei segmentation and classification model.

Scientific reports
Image processing and pattern recognition methods have recently been extensively implemented in histopathological images (HIs). These computer-aided techniques are aimed at detecting the attentive biological markers for assisting the final cancer grad...

A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides.

Communications biology
Mitotic activity is an important feature for grading several cancer types. However, counting mitotic figures (cells in division) is a time-consuming and laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incor...

[Impact of artificial intelligence on the evolution of clinical practices in oncology: Focus on language models].

Bulletin du cancer
Artificial intelligence (AI) is addressing many expectations for healthcare practitioners and patients in oncology. It has the potential to deeply transform medical practices as we know them today: improving early diagnosis by analysing large quantit...

SyntheVAEiser: augmenting traditional machine learning methods with VAE-based gene expression sample generation for improved cancer subtype predictions.

Genome biology
The accuracy of machine learning methods is often limited by the amount of training data that is available. We proposed to improve machine learning training regimes by augmenting datasets with synthetically generated samples. We present a method for ...

Novel artificial intelligence-based identification of drug-gene-disease interaction using protein-protein interaction.

BMC bioinformatics
The evaluation of drug-gene-disease interactions is key for the identification of drugs effective against disease. However, at present, drugs that are effective against genes that are critical for disease are difficult to identify. Following a diseas...

Machine learning-assisted pattern recognition and imaging of multiplexed cancer cells a porphyrin-embedded dendrimer array.

Journal of materials chemistry. B
Early cancer detection plays a vital role in improving the survival rate of cancer patients, underscoring the importance of developing cancer detection methods. However, it is a great challenge to achieve simple, rapid, and accurate methods for simul...

Deep profiling of gene expression across 18 human cancers.

Nature biomedical engineering
Clinical and biological information in large datasets of gene expression across cancers could be tapped with unsupervised deep learning. However, difficulties associated with biological interpretability and methodological robustness have made this im...

Advancing miRNA cancer research through artificial intelligence: from biomarker discovery to therapeutic targeting.

Medical oncology (Northwood, London, England)
MicroRNAs (miRNAs), a class of small non-coding RNAs, play a vital role in regulating gene expression at the post-transcriptional level. Their discovery has profoundly impacted therapeutic strategies, particularly in cancer treatment, where RNA thera...

Machine learning and SHAP value interpretation for predicting comorbidity of cardiovascular disease and cancer with dietary antioxidants.

Redox biology
OBJECTIVE: To develop and validate a machine learning model incorporating dietary antioxidants to predict cardiovascular disease (CVD)-cancer comorbidity and to elucidate the role of antioxidants in disease prediction.