There is a need for non-invasive, sensitive, real-time, and user-friendly optical devices integrated with artificial intelligence (AI) based tools for the detection of oral mucosal lesions at early stage. Research on the development of optical device...
Early cancer detection plays a vital role in improving the survival rate of cancer patients, underscoring the importance of developing cancer detection methods. However, it is a great challenge to achieve simple, rapid, and accurate methods for simul...
Given the crucial role of thiols in maintaining normal physiological functions, it is essential to establish a high-throughput and sensitive analytical method to identify and quantify various thiols accurately. Inspired by the iron porphyrin active c...
BACKGROUND: Oncological analysis is important in tumor diagnosis. We constructed a dual-fluorescence and binary visual analysis system for circulating tumor cells (CTCs) using the folate receptor as a biomarker, combined with hybridization chain reac...
Photodiagnosis and photodynamic therapy
Sep 5, 2022
PURPOSE: To assess the prediction of the response to photodynamic therapy (PDT) in chronic central serous chorioretinopathy (CSCR) based on spectral-domain optical coherence tomography (SD-OCT) images using deep learning (DL).
A fluorescent aptasensor based on porphyrin-based covalent organic framework (p-COF) and carbon dots (CDs) was constructed for detecting vascular endothelial growth factor 165 (VEGF) and for imaging of the breast cancer cell line Michigan cancer foun...
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Jun 1, 2025
Understanding the relationship between molecular structure and bioactivity is crucial for optimizing porphyrin-based therapeutics. By integrating cheminformatics techniques with machine learning models, our work enables the efficient classification o...
Journal of chemical information and modeling
May 12, 2025
Porphyrins are involved in numerous and very different chemical and biological processes, due to the sensitivity of their application-relevant properties to subtle structural changes. Applying modern machine learning methodology is very appealing for...
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