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Porphyrins

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Hybrid chain reaction and selective recognition-based homogeneous dual-fluorescence analysis of circulating tumor cells in clinical ovarian cancer samples.

Analytica chimica acta
BACKGROUND: Oncological analysis is important in tumor diagnosis. We constructed a dual-fluorescence and binary visual analysis system for circulating tumor cells (CTCs) using the folate receptor as a biomarker, combined with hybridization chain reac...

Porphyrin-based covalent organic framework as bioplatfrom for detection of vascular endothelial growth factor 165 through fluorescence resonance energy transfer.

Talanta
A fluorescent aptasensor based on porphyrin-based covalent organic framework (p-COF) and carbon dots (CDs) was constructed for detecting vascular endothelial growth factor 165 (VEGF) and for imaging of the breast cancer cell line Michigan cancer foun...

Data-Driven Insights into Porphyrin Geometry: Interpretable AI for Non-Planarity and Aromaticity Analyses.

Journal of chemical information and modeling
Porphyrins are involved in numerous and very different chemical and biological processes, due to the sensitivity of their application-relevant properties to subtle structural changes. Applying modern machine learning methodology is very appealing for...

Prediction of the response to photodynamic therapy in patients with chronic central serous chorioretinopathy based on optical coherence tomography using deep learning.

Photodiagnosis and photodynamic therapy
PURPOSE: To assess the prediction of the response to photodynamic therapy (PDT) in chronic central serous chorioretinopathy (CSCR) based on spectral-domain optical coherence tomography (SD-OCT) images using deep learning (DL).

Bioinspired Iron Porphyrin Covalent Organic Frameworks-Based Nanozymes Sensor Array: Machine Learning-Assisted Identification and Detection of Thiols.

ACS applied materials & interfaces
Given the crucial role of thiols in maintaining normal physiological functions, it is essential to establish a high-throughput and sensitive analytical method to identify and quantify various thiols accurately. Inspired by the iron porphyrin active c...

Machine learning-assisted pattern recognition and imaging of multiplexed cancer cells a porphyrin-embedded dendrimer array.

Journal of materials chemistry. B
Early cancer detection plays a vital role in improving the survival rate of cancer patients, underscoring the importance of developing cancer detection methods. However, it is a great challenge to achieve simple, rapid, and accurate methods for simul...

Integration of the fluorescence based portable device with the AI tools for the real-time monitoring of oral mucosal lesions.

Scientific reports
There is a need for non-invasive, sensitive, real-time, and user-friendly optical devices integrated with artificial intelligence (AI) based tools for the detection of oral mucosal lesions at early stage. Research on the development of optical device...