BACKGROUND: Early diagnosis is vital for increasing the rates of curing diseases and patient survival in medicine. With the advancement of biotechnology, the types of bioomics data are increasing. The integration of multiomics data can provide more c...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Mar 7, 2025
Understanding the prognosis of cancer patients is crucial for enabling precise diagnosis and treatment by clinical practitioners. Multimodal fusion models based on artificial intelligence (AI) offer a comprehensive depiction of the tumor heterogeneit...
To assess the efficacy of a deep learning platform for managing symptoms in chemotherapy patients, aiming to enhance their quality of life. A non-randomized controlled trial was conducted from September 2022 to March 2024, involving 144 chemotherapy ...
The quantification of circulating tumour DNA (ctDNA) in blood enables non-invasive surveillance of cancer progression. Here we show that a deep-learning model can accurately quantify ctDNA from the density distribution of cell-free DNA-fragment lengt...
The integration of artificial intelligence (AI) into oncology promises to revolutionize cancer care. In this Review, we discuss ten AI hallmarks in precision oncology, organized into three groups: (1) cancer prevention and diagnosis, encompassing can...
Cancer is a severe threat to public health. Early diagnosis of disease is critical, but the lack of experts in this field, the personal assessment process, the clinical workload, and the high level of similarity in disease classes make it difficult. ...
IEEE journal of biomedical and health informatics
Mar 6, 2025
A thorough understanding of cell-line drug response mechanisms is crucial for drug development, repurposing, and resistance reversal. While targeted anticancer therapies have shown promise, not all cancers have well-established biomarkers to stratify...
IEEE journal of biomedical and health informatics
Mar 6, 2025
Cancer is a multifaceted disease that results from co-mutations of multi biological molecules. A promising strategy for cancer therapy involves in exploiting the phenomenon of Synthetic Lethality (SL) by targeting the SL partner of cancer gene. Since...
The tumor-homing peptides (THPs) have emerged as one of the attractive resources for targeted cancer therapy, being able to bind and penetrate tumor cells selectively while ignoring adjacent healthy tissues. Therefore, the computational models to pre...
Predicting the response of a cancer cell line to a therapeutic drug is pivotal for personalized medicine. Despite numerous deep learning methods that have been developed for drug response prediction, integrating diverse information about biological e...
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