AIMC Topic: Neural Networks, Computer

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Facial Recognition Neural Networks Confirm Success of Facial Feminization Surgery.

Plastic and reconstructive surgery
BACKGROUND: Male-to-female transgender patients desire to be identified, and treated, as female, in public and social settings. Facial feminization surgery entails a combination of highly visible changes in facial features. To study the effectiveness...

Ensuring electronic medical record simulation through better training, modeling, and evaluation.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Electronic medical records (EMRs) can support medical research and discovery, but privacy risks limit the sharing of such data on a wide scale. Various approaches have been developed to mitigate risk, including record simulation via genera...

Extracting medications and associated adverse drug events using a natural language processing system combining knowledge base and deep learning.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Detecting adverse drug events (ADEs) and medications related information in clinical notes is important for both hospital medical care and medical research. We describe our clinical natural language processing (NLP) system to automatically...

Identifying relations of medications with adverse drug events using recurrent convolutional neural networks and gradient boosting.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: To develop a natural language processing system that identifies relations of medications with adverse drug events from clinical narratives. This project is part of the 2018 n2c2 challenge.

A Drug Decision Support System for Developing a Successful Drug Candidate Using Machine Learning Techniques.

Current computer-aided drug design
BACKGROUND: Virtual screening of candidate drug molecules using machine learning techniques plays a key role in pharmaceutical industry to design and discovery of new drugs. Computational classification methods can determine drug types according to t...

Adverse drug events and medication relation extraction in electronic health records with ensemble deep learning methods.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Identification of drugs, associated medication entities, and interactions among them are crucial to prevent unwanted effects of drug therapy, known as adverse drug events. This article describes our participation to the n2c2 shared-task in...

Adverse drug event and medication extraction in electronic health records via a cascading architecture with different sequence labeling models and word embeddings.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: An adverse drug event (ADE) refers to an injury resulting from medical intervention related to a drug including harm caused by drugs or from the usage of drugs. Extracting ADEs from clinical records can help physicians associate adverse ev...

DeePaC: predicting pathogenic potential of novel DNA with reverse-complement neural networks.

Bioinformatics (Oxford, England)
MOTIVATION: We expect novel pathogens to arise due to their fast-paced evolution, and new species to be discovered thanks to advances in DNA sequencing and metagenomics. Moreover, recent developments in synthetic biology raise concerns that some stra...

Development of a periodontitis risk assessment model for primary care providers in an interdisciplinary setting.

Technology and health care : official journal of the European Society for Engineering and Medicine
BACKGROUND: Periodontitis (PD), a form of gum disease, is a major public health concern as it is globally prevalent and harms both individual quality of life and economic productivity. Global cost in lost productivity is estimated at US$54 billion an...

HUNER: improving biomedical NER with pretraining.

Bioinformatics (Oxford, England)
MOTIVATION: Several recent studies showed that the application of deep neural networks advanced the state-of-the-art in named entity recognition (NER), including biomedical NER. However, the impact on performance and the robustness of improvements cr...