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Neural Pathways

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Classifying heterogeneous presentations of PTSD via the default mode, central executive, and salience networks with machine learning.

NeuroImage. Clinical
Intrinsic connectivity networks (ICNs), including the default mode network (DMN), the central executive network (CEN), and the salience network (SN) have been shown to be aberrant in patients with posttraumatic stress disorder (PTSD). The purpose of ...

A double-hit of stress and low-grade inflammation on functional brain network mediates posttraumatic stress symptoms.

Nature communications
Growing evidence indicates a reciprocal relationship between low-grade systemic inflammation and stress exposure towards increased vulnerability to neuropsychiatric disorders, including posttraumatic stress disorder (PTSD). However, the neural correl...

Nonlinear ICA of fMRI reveals primitive temporal structures linked to rest, task, and behavioral traits.

NeuroImage
Accumulating evidence from whole brain functional magnetic resonance imaging (fMRI) suggests that the human brain at rest is functionally organized in a spatially and temporally constrained manner. However, because of their complexity, the fundamenta...

The NanoZoomer artificial intelligence connectomics pipeline for tracer injection studies of the marmoset brain.

Brain structure & function
We describe our connectomics pipeline for processing anterograde tracer injection data for the brain of the common marmoset (Callithrix jacchus). Brain sections were imaged using a batch slide scanner (NanoZoomer 2.0-HT) and we used artificial intell...

Working memory load-dependent changes in cortical network connectivity estimated by machine learning.

NeuroImage
Working memory engages multiple distributed brain networks to support goal-directed behavior and higher order cognition. Dysfunction in working memory has been associated with cognitive impairment in neuropsychiatric disorders. It is important to cha...

Neural dynamics of perceptual inference and its reversal during imagery.

eLife
After the presentation of a visual stimulus, neural processing cascades from low-level sensory areas to increasingly abstract representations in higher-level areas. It is often hypothesised that a reversal in neural processing underlies the generatio...

Outcome prediction with resting-state functional connectivity after cardiac arrest.

Scientific reports
Predicting outcome in comatose patients after successful cardiopulmonary resuscitation is challenging. Our primary aim was to assess the potential contribution of resting-state-functional magnetic resonance imaging (RS-fMRI) in predicting neurologica...

A new method to predict anomaly in brain network based on graph deep learning.

Reviews in the neurosciences
Functional magnetic resonance imaging a neuroimaging technique which is used in brain disorders and dysfunction studies, has been improved in recent years by mapping the topology of the brain connections, named connectopic mapping. Based on the fact ...

Pyramid-Shape Crossings and Intercrossing Fibers Are Key Elements for Construction of the Neural Network in the Superficial White Matter of the Human Cerebrum.

Cerebral cortex (New York, N.Y. : 1991)
Structural analysis of the superficial white matter is prerequisite for the understanding of highly integrated functions of the human cerebral cortex. However, the principal components, U-fibers, have been regarded as simple wires to connect adjacent...