AIMC Topic: Neurogenesis

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Impaired neurogenesis of the dentate gyrus is associated with pattern separation deficits: A computational study.

Journal of integrative neuroscience Sep 21, 2016
The separation of input patterns received from the entorhinal cortex (EC) by the dentate gyrus (DG) is a well-known critical step of information processing in the hippocampus. Although the role of interneurons in separation pattern efficiency of the ...
Neural Networks, Computer Animals Synaptic Transmission Dentate Gyrus Alzheimer Disease Neurogenesis Models, Neurological Neurons
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Computational Modeling of Adult Neurogenesis.

Cold Spring Harbor perspectives in biology Apr 1, 2016
The restriction of adult neurogenesis to only a handful of regions of the brain is suggestive of some shared requirement for this dramatic form of structural plasticity. However, a common driver across neurogenic regions has not yet been identified. ...
Computer Simulation Nerve Net Neural Networks, Computer Neurogenesis Dentate Gyrus
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Genes with high penetrance for syndromic and non-syndromic autism typically function within the nucleus and regulate gene expression.

Molecular autism Mar 15, 2016
BACKGROUND: Intellectual disability (ID), autism, and epilepsy share frequent yet variable comorbidities with one another. In order to better understand potential genetic divergence underlying this variable risk, we studied genes responsible for mono...
Penetrance Neurogenesis Intellectual Disability Body Patterning Chromatin Assembly and Disassembly Risk Gene Ontology Gene Expression Regulation Autistic Disorder Humans Autism Spectrum Disorder Comorbidity Protein Interaction Maps Nerve Tissue Proteins Epilepsy Syndrome Cell Nucleus Nuclear Proteins Databases, Genetic Genetic Association Studies Epigenomics
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Dynamic role of adult-born dentate granule cells in memory processing.

Current opinion in neurobiology Jun 19, 2015
Throughout the adult life of all mammals including humans, new neurons are incorporated to the dentate gyrus of the hippocampus. During a critical window that lasts about two weeks, adult-born immature neurons are more excitable and plastic than matu...
Neurogenesis Humans Dentate Gyrus Nerve Net Animals Neurons Memory Neural Networks, Computer Adult
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Developmental time windows for axon growth influence neuronal network topology.

Biological cybernetics Jan 30, 2015
Early brain connectivity development consists of multiple stages: birth of neurons, their migration and the subsequent growth of axons and dendrites. Each stage occurs within a certain period of time depending on types of neurons and cortical layers....
Time Axons Caenorhabditis elegans Animals Synapses Embryo, Nonmammalian Neurogenesis Models, Neurological Cell Division Neural Networks, Computer Computer Simulation
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Improving Recall in Sparse Associative Memories That Use Neurogenesis.

Neural computation Feb 14, 2025
The creation of future low-power neuromorphic solutions requires specialist spiking neural network (SNN) algorithms that are optimized for neuromorphic settings. One such algorithmic challenge is the ability to recall learned patterns from their nois...
Models, Neurological Neurons Algorithms Animals Mental Recall Association Learning Memory Neurogenesis Humans Neural Networks, Computer
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