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Neuroimaging

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Neural networks for parameter estimation in microstructural MRI: Application to a diffusion-relaxation model of white matter.

NeuroImage
Specific features of white matter microstructure can be investigated by using biophysical models to interpret relaxation-diffusion MRI brain data. Although more intricate models have the potential to reveal more details of the tissue, they also incur...

Explainable artificial intelligence based analysis for interpreting infant fNIRS data in developmental cognitive neuroscience.

Communications biology
In the last decades, non-invasive and portable neuroimaging techniques, such as functional near infrared spectroscopy (fNIRS), have allowed researchers to study the mechanisms underlying the functional cognitive development of the human brain, thus f...

Automatic Symmetry Detection From Brain MRI Based on a 2-Channel Convolutional Neural Network.

IEEE transactions on cybernetics
Symmetry detection is a method to extract the ideal mid-sagittal plane (MSP) from brain magnetic resonance (MR) images, which can significantly improve the diagnostic accuracy of brain diseases. In this article, we propose an automatic symmetry detec...

Automated claustrum segmentation in human brain MRI using deep learning.

Human brain mapping
In the last two decades, neuroscience has produced intriguing evidence for a central role of the claustrum in mammalian forebrain structure and function. However, relatively few in vivo studies of the claustrum exist in humans. A reason for this may ...

Deep Learning-Based Automated Thrombolysis in Cerebral Infarction Scoring: A Timely Proof-of-Principle Study.

Stroke
BACKGROUND AND PURPOSE: Mechanical thrombectomy is an established procedure for treatment of acute ischemic stroke. Mechanical thrombectomy success is commonly assessed by the Thrombolysis in Cerebral Infarction (TICI) score, assigned by visual inspe...

MRI-Based Machine Learning Prediction Framework to Lateralize Hippocampal Sclerosis in Patients With Temporal Lobe Epilepsy.

Neurology
BACKGROUND AND OBJECTIVES: MRI fails to reveal hippocampal pathology in 30% to 50% of temporal lobe epilepsy (TLE) surgical candidates. To address this clinical challenge, we developed an automated MRI-based classifier that lateralizes the side of co...

DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease.

NeuroImage
Measures of change in hippocampal volume derived from longitudinal MRI are a well-studied biomarker of disease progression in Alzheimer's disease (AD) and are used in clinical trials to track therapeutic efficacy of disease-modifying treatments. Howe...

Strategies for feature extraction from structural brain imaging in lesion-deficit modelling.

Human brain mapping
High-dimensional modelling of post-stroke deficits from structural brain imaging is highly relevant to basic cognitive neuroscience and bears the potential to be translationally used to guide individual rehabilitation measures. One strategy to optimi...

Accounting for symptom heterogeneity can improve neuroimaging models of antidepressant response after electroconvulsive therapy.

Human brain mapping
Depression symptom heterogeneity limits the identifiability of treatment-response biomarkers. Whether improvement along dimensions of depressive symptoms relates to separable neural networks remains poorly understood. We build on work describing thre...