AIMC Topic: Neurons

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Uncovering memorization effect in the presence of spurious correlations.

Nature communications Jul 1, 2025
Machine learning models often rely on simple spurious features - patterns in training data that correlate with targets but are not causally related to them, like image backgrounds in foreground classification. This reliance typically leads to imbalan...
Neurons Memory Humans Neural Networks, Computer Machine Learning
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Brainstem noradrenergic modulation of the kisspeptin neuron GnRH pulse generator in mice.

Nature communications Jul 1, 2025
Brainstem noradrenaline (NA) neurons modulate the activity of many neural networks including those responsible for the control of fertility. Using brain slice electrophysiology, we demonstrate that the arcuate nucleus kisspeptin (ARN) neurons, recent...
Female Animals Male Neurons Gonadotropin-Releasing Hormone Kisspeptins Mice Mice, Inbred C57BL Norepinephrine Arcuate Nucleus of Hypothalamus Adrenergic Neurons Brain Stem Locus Coeruleus
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A simplified minimodel of visual cortical neurons.

Nature communications Jul 1, 2025
Artificial neural networks (ANNs) have been shown to predict neural responses in primary visual cortex (V1) better than classical models. However, this performance often comes at the expense of simplicity and interpretability. Here we introduce a new...
Animals Primary Visual Cortex Neurons Neural Networks, Computer Mice Photic Stimulation Models, Neurological Visual Cortex
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Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior.

Nature communications Jul 1, 2025
Feeding is an innate behavior critical for survival but is also influenced by many non-nutritional factors such as emotion, social context and environmental conditions. Recently, tuberal nucleus somatostatin (SST) neurons have been identified as a ke...
Male Mice Mice, Inbred C57BL Brain Neurons Nerve Net Animals Feeding Behavior Somatostatin Neural Pathways Agouti-Related Protein
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Neurons throughout the brain embed robust signatures of their anatomical location into spike trains.

eLife Jun 27, 2025
Neurons in the brain are known to encode diverse information through their spiking activity, primarily reflecting external stimuli and internal states. However, whether individual neurons also embed information about their own anatomical location wit...
Action Potentials Mice, Inbred C57BL Neurons Male Mice Machine Learning Models, Neurological Brain Animals
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Optogenetic neural spheroids excite primary neural network.

Journal of neural engineering Jun 26, 2025
Optical stimulation ofneurons requires prior transfection with light gated ion channels. This additional step brings complexity and requires optimization. Simplification of the process will ease the undertaking of studies on biological neural network...
Neurons Nerve Net Spheroids, Cellular Cells, Cultured Optogenetics Animals Embryonic Stem Cells Mice
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Predictive learning rules generate a cortical-like replay of probabilistic sensory experiences.

eLife Jun 16, 2025
The brain is thought to construct an optimal internal model representing the probabilistic structure of the environment accurately. Evidence suggests that spontaneous brain activity gives such a model by cycling through activity patterns evoked by pr...
Cerebral Cortex Nerve Net Models, Neurological Learning Macaca mulatta Action Potentials Animals Neurons
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Bio-Inspired spiking tactile sensing system for robust texture recognition across varying scanning speeds in passive touch.

Biological cybernetics Jun 14, 2025
Tactile sensing plays a crucial role in texture recognition, but variations in scanning speed pose a significant challenge for accurate discrimination. Previous studies have demonstrated that scanning speed alters the frequency of texture-induced vib...
Touch Touch Perception Mechanoreceptors Humans Animals Action Potentials Models, Neurological Neurons
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Visualizing nuclear pore complex plasticity with pan-expansion microscopy.

The Journal of cell biology Jun 12, 2025
The exploration of cell-type and environmentally responsive nuclear pore complex (NPC) plasticity requires new, accessible tools. Using pan-expansion microscopy (pan-ExM), NPCs were identified by machine learning-facilitated segmentation. They exhibi...
C9orf72 Protein Nuclear Envelope Nuclear Pore Neurons Microscopy Humans Induced Pluripotent Stem Cells Membrane Glycoproteins Amyotrophic Lateral Sclerosis
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A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the ventral nerve cord.

eLife Jun 10, 2025
Understanding developmental changes in neuronal lineages is crucial to elucidate how they assemble into functional neural networks. Studies investigating nervous system development in model systems have only focused on select regions of the CNS due t...
Neurons Drosophila Proteins Behavior, Animal Drosophila melanogaster Nerve Net Gene Library Animals Transcription Factors Cell Lineage Drosophila Optogenetics
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