AIMC Topic: Sclera

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Analysis of 2-dimensional regional differences in the peripapillary scleral fibroblast cytoskeleton of normotensive and hypertensive mouse eyes.

Scientific reports Jul 1, 2025
These studies aimed to study the mechanisms of glaucomatous peripapillary scleral (PPS) remodeling by investigating IOP-induced changes in fibroblast actin-collagen alignment and nuclear morphology in mouse PPS. Cryosections from the optic nerve head...
Male Mice Disease Models, Animal Mice, Inbred C57BL Glaucoma Intraocular Pressure Animals Actins Cytoskeleton Ocular Hypertension Sclera Fibroblasts Collagen Optic Disk
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Remote and low-cost intraocular pressure monitoring by deep learning of speckle patterns.

Journal of biomedical optics Mar 29, 2024
SIGNIFICANCE: Glaucoma, a leading cause of global blindness, disproportionately affects low-income regions due to expensive diagnostic methods. Affordable intraocular pressure (IOP) measurement is crucial for early detection, especially in low- and m...
Glaucoma Tonometry, Ocular Humans Intraocular Pressure Swine Sclera Animals Deep Learning
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Reproducibility of deep learning based scleral spur localisation and anterior chamber angle measurements from anterior segment optical coherence tomography images.

The British journal of ophthalmology Jan 28, 2022
AIMS: To apply a deep learning model for automatic localisation of the scleral spur (SS) in anterior segment optical coherence tomography (AS-OCT) images and compare the reproducibility of anterior chamber angle (ACA) width between deep learning loca...
Humans Reproducibility of Results Middle Aged Deep Learning Tomography, Optical Coherence Iris Aged Cross-Sectional Studies Intraocular Pressure Sclera Anterior Eye Segment Anterior Chamber Glaucoma, Angle-Closure Gonioscopy
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Deep Learning Algorithm for Automated Detection of Polycystic Ovary Syndrome Using Scleral Images.

Frontiers in endocrinology Jan 27, 2022
The high prevalence of polycystic ovary syndrome (PCOS) among reproductive-aged women has attracted more and more attention. As a common disorder that is likely to threaten women's health physically and mentally, the detection of PCOS is a growing pu...
Adult Deep Learning Image Processing, Computer-Assisted Polycystic Ovary Syndrome Sclera Humans Algorithms Female
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Open-source deep learning-based automatic segmentation of mouse Schlemm's canal in optical coherence tomography images.

Experimental eye research Nov 16, 2021
The purpose of this study was to develop an automatic deep learning-based approach and corresponding free, open-source software to perform segmentation of the Schlemm's canal (SC) lumen in optical coherence tomography (OCT) scans of living mouse eyes...
Sclera Anterior Eye Segment Glaucoma, Open-Angle Tonometry, Ocular Algorithms Intraocular Pressure Animals Mice, Inbred C57BL Tomography, Optical Coherence Deep Learning Neural Networks, Computer Mice
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Adaptive Control Improves Sclera Force Safety in Robot-Assisted Eye Surgery: A Clinical Study.

IEEE transactions on bio-medical engineering Oct 19, 2021
The integration of robotics into retinal microsurgery leads to a reduction in surgeon perception of tool-to-tissue interaction forces. This blunting of human tactile sensory input, which is due to the inflexible mass and large inertia of the robotic ...
Retina Sclera Robotics Microsurgery Robotic Surgical Procedures Humans
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Machine learning prediction of pathologic myopia using tomographic elevation of the posterior sclera.

Scientific reports Mar 26, 2021
Qualitative analysis of fundus photographs enables straightforward pattern recognition of advanced pathologic myopia. However, it has limitations in defining the classification of the degree or extent of early disease, such that it may be biased by s...
Humans Biomarkers Fundus Oculi Optic Disk Middle Aged Retrospective Studies Fovea Centralis Myopia, Degenerative Support Vector Machine Female Sclera Male Tomography, Optical Coherence Axial Length, Eye
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Robotic Retinal Surgery Impacts on Scleral Forces: In Vivo Study.

Translational vision science & technology Sep 1, 2020
PURPOSE: This study aims to map force interaction between instrument and sclera of in vivo rabbits during retinal procedures, and verify if a robotic active force control could prevent unwanted increase of forces on the sclera.
Rabbits Retina Sclera Animals Microsurgery Robotics Robotic Surgical Procedures
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Deep Neural Network for Scleral Spur Detection in Anterior Segment OCT Images: The Chinese American Eye Study.

Translational vision science & technology Mar 30, 2020
PURPOSE: To develop a deep neural network that detects the scleral spur in anterior segment optical coherence tomography (AS-OCT) images.
Humans Neural Networks, Computer Asian Los Angeles Glaucoma, Angle-Closure Sclera
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Force classification during robotic interventions through simulation-trained neural networks.

International journal of computer assisted radiology and surgery Aug 16, 2019
PURPOSE: Intravitreal injection is among the most frequent treatment strategies for chronic ophthalmic diseases. The last decade has seen a serious increase in the number of intravitreal injections, and with it, adverse effects and drawbacks. To tack...
Diagnostic Techniques, Ophthalmological Swine Computer Simulation Robotic Surgical Procedures Humans Tomography, Optical Coherence Mechanical Phenomena Reproducibility of Results Animals Bayes Theorem Sclera Intravitreal Injections Image Processing, Computer-Assisted Models, Theoretical Neural Networks, Computer Machine Learning
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