AIMC Topic: Organs at Risk

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Knowledge-based radiation therapy (KBRT) treatment planning versus planning by experts: validation of a KBRT algorithm for prostate cancer treatment planning.

Radiation oncology (London, England)
BACKGROUND: A knowledge-based radiation therapy (KBRT) treatment planning algorithm was recently developed. The purpose of this work is to investigate how plans that are generated with the objective KBRT approach compare to those that rely on the jud...

Evaluation of a knowledge-based planning solution for head and neck cancer.

International journal of radiation oncology, biology, physics
PURPOSE: Automated and knowledge-based planning techniques aim to reduce variations in plan quality. RapidPlan uses a library consisting of different patient plans to make a model that can predict achievable dose-volume histograms (DVHs) for new pati...

Automatic contour quality assurance using deep-learning based contours.

Physics in medicine and biology
Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One such approach is to use two independent auto-contouring models and compare them geometrically for acceptability. This is not effective because g...

U-Attention-Net: a deep learning automatic delineation model for parotid glands in head and neck cancer organs at risk on radiotherapy localization computed tomography images.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
OBJECTIVE: This study aimed to develop a novel deep learning model, U-Attention-Net (UA-Net), for precise segmentation of parotid glands on radiotherapy localization CT images.

Deep learning-based auto-contouring of organs/structures-at-risk for pediatric upper abdominal radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSES: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets.

Automated field-in-field planning for tangential breast radiation therapy based on digitally reconstructed radiograph.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
BACKGROUND: The tangential field-in-field (FIF) technique is a widely used method in breast radiation therapy, known for its efficiency and the reduced number of fields required in treatment planning. However, it is labor-intensive, requiring manual ...

Virtual monochromatic image-based automatic segmentation strategy using deep learning method.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
BACKGROUND AND PURPOSE: The image quality of single-energy CT (SECT) limited the accuracy of automatic segmentation. Dual-energy CT (DECT) may potentially improve automatic segmentation yet the performance and strategy have not been investigated thor...

On factors that influence deep learning-based dose prediction of head and neck tumors.

Physics in medicine and biology
This study investigates key factors influencing deep learning-based dose prediction models for head and neck cancer radiation therapy. The goal is to evaluate model accuracy, robustness, and computational efficiency, and to identify key components ne...

Deep learning-powered radiotherapy dose prediction: clinical insights from 622 patients across multiple sites tumor at a single institution.

Radiation oncology (London, England)
PURPOSE: Accurate pre-treatment dose prediction is essential for efficient radiotherapy planning. Although deep learning models have advanced automated dose distribution, comprehensive multi-tumor analyses remain scarce. This study assesses deep lear...

Patient-specific uncertainty calibration of deep learning-based autosegmentation networks for adaptive MRI-guided lung radiotherapy.

Physics in medicine and biology
Uncertainty assessment of deep learning autosegmentation (DLAS) models can support contour corrections in adaptive radiotherapy (ART), e.g. by utilizing Monte Carlo Dropout (MCD) uncertainty maps. However, poorly calibrated uncertainties at the patie...