AIMC Topic: Organs at Risk

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The implementation of knowledge-based planning with partial OAR contours for prostate radiotherapy.

Journal of applied clinical medical physics
PURPOSE: Intra- and inter-observer contour uncertainty is a continuous challenge in treatment planning for radiotherapy. Our proposed solution to address this challenge is the use of partial contours for treatment planning, focusing on uninvolved or ...

Automating the optimization of proton PBS treatment planning for head and neck cancers using policy gradient-based deep reinforcement learning.

Medical physics
BACKGROUND: Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of potentially conflicting planning objectives are involved. Deep reinforcement le...

Deep learning-based synthetic CT for dosimetric monitoring of combined conventional radiotherapy and lattice boost in large lung tumors.

Radiation oncology (London, England)
PURPOSE: Conventional radiotherapy (CRT) has limited local control and poses a high risk of severe toxicity in large lung tumors. This study aimed to develop an integrated treatment plan that combines CRT with lattice boost radiotherapy (LRT) and mon...

Evaluation of AI-based auto-contouring tools in radiotherapy: A single-institution study.

Journal of applied clinical medical physics
BACKGROUND: Accurate delineation of organs at risk (OARs) is crucial yet time-consuming in the radiotherapy treatment planning workflow. Modern artificial intelligence (AI) technologies had made automation of OAR contouring feasible. This report deta...

Under-representation for Female Pelvis Cancers in Commercial Auto-segmentation Solutions and Open-source Imaging Datasets.

Clinical oncology (Royal College of Radiologists (Great Britain))
AIM: Artificial intelligence (AI) based auto-segmentation aids radiation therapy (RT) workflows and is being adopted in clinical environments facilitated by the increased availability of commercial solutions for organs at risk (OARs). In addition, op...

Automatic segmentation of MRI images for brain radiotherapy planning using deep ensemble learning.

Biomedical physics & engineering express
This study aimed to develop and evaluate an efficient method to automatically segment T1- and T2-weighted brain magnetic resonance imaging (MRI) images. We specifically compared the segmentation performance of individual convolutional neural network ...

A qualitative, quantitative and dosimetric evaluation of a machine learning-based automatic segmentation method in treatment planning for gastric cancer.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To investigate the performance of a machine learning-based segmentation method for treatment planning of gastric cancer.

Generalizability, robustness, and correction bias of segmentations of thoracic organs at risk in CT images.

European radiology
OBJECTIVE: This study aims to assess and compare two state-of-the-art deep learning approaches for segmenting four thoracic organs at riskĀ (OAR)-the esophagus, trachea, heart, and aorta-in CT images in the context of radiotherapy planning.

Automated treatment planning with deep reinforcement learning for head-and-neck (HN) cancer intensity modulated radiation therapy (IMRT).

Physics in medicine and biology
To develop a deep reinforcement learning (DRL) agent to self-interact with the treatment planning system to automatically generate intensity modulated radiation therapy (IMRT) treatment plans for head-and-neck (HN) cancer with consistent organ-at-ris...

Machine learning based radiomics model to predict radiotherapy induced cardiotoxicity in breast cancer.

Journal of applied clinical medical physics
PURPOSE: Cardiotoxicity is one of the major concerns in breast cancer treatment, significantly affecting patient outcomes. To improve the likelihood of favorable outcomes for breast cancer survivors, it is essential to carefully balance the potential...