BACKGROUND: Machine learning (ML) has been investigated for its predictive value in knee osteoarthritis (KOA) progression. However, systematic evidence on the effectiveness of ML is still lacking, posing a challenge to precision prevention.
BACKGROUND: Symptomatic knee osteoarthritis (KOA) imposes a substantial global health and economic burden. Although chronological age (CA) is a key risk factor, it poorly reflects interindividual aging heterogeneity. Biological age (BA), which is qua...
Gut dysbiosis and systemic inflammation are increasingly recognized in the pathogenesis of knee osteoarthritis (OA). While altered gut microbiota profiles have been reported, the link between specific microbial taxa and physical functioning in OA pat...
Early detection of knee osteoarthritis (KOA) is essential to improve treatment outcomes and reduce its long-term impact. However, early diagnosis of KOA (EKOA) remains difficult due to the absence of standardised criteria and the subtle or intermitte...
OBJECTIVES: To develop a cascaded machine learning model based on MRI radiomics features from cartilage and subchondral bone to predict the incidence and progression of knee osteoarthritis (KOA), thereby addressing the need for early intervention in ...
INTRODUCTION: Knee osteoarthritis (KOA) is a prevalent degenerative joint disorder affecting a significant portion of the elderly population. Despite the availability of various non-surgical and pharmacological treatments, their effectiveness is ofte...
We evaluated the effectiveness of magnetic resonance imaging (MRI)-based subregional texture analysis (TA) models for classifying knee osteoarthritis (OA) severity grades by compartment. We identified 122 MR images of 121 patients with knee OA (mild-...
Knee Osteoarthritis (K-OA) is characterized as a progressive joint condition with global prevalence, exhibiting deterioration over time and impacting a significant portion of the population. It happens because joints wear out slowly. The main reason ...
Precise and rapid identification of knee osteoarthritis (OA) is essential for efficient management and therapy planning. Conventional diagnostic techniques frequently depend on subjective interpretation, which have shortcomings, particularly during t...
Knee osteoarthritis (KOA) is a prevalent, debilitating chronic joint disease characterized by pain, stiffness, and functional limitations. Non-pharmacological rehabilitation is a fundamental management strategy. This narrative review synthesizes evid...
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