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Osteoporosis

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Deep learning for screening primary osteopenia and osteoporosis using spine radiographs and patient clinical covariates in a Chinese population.

Frontiers in endocrinology
PURPOSE: Many high-risk osteopenia and osteoporosis patients remain undiagnosed. We proposed to construct a convolutional neural network model for screening primary osteopenia and osteoporosis based on the lumbar radiographs, and to compare the diagn...

Deep-learning image reconstruction for image quality evaluation and accurate bone mineral density measurement on quantitative CT: A phantom-patient study.

Frontiers in endocrinology
BACKGROUND AND PURPOSE: To investigate the image quality and accurate bone mineral density (BMD) on quantitative CT (QCT) for osteoporosis screening by deep-learning image reconstruction (DLIR) based on a multi-phantom and patient study.

Osteoporosis screening support system from panoramic radiographs using deep learning by convolutional neural network.

Dento maxillo facial radiology
OBJECTIVES: This study was performed to develop computer-aided screening systems that could predict osteoporosis. The systems were constructed using panoramic radiographs of women aged ≥ 50 years through three types of deep convolutional neural netwo...

Can machine learning predict pharmacotherapy outcomes? An application study in osteoporosis.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: The specific aim of this study is to develop machine learning models as a clinical approach for personalized treatment of osteoporosis. The model performance on outcome prediction was compared between four machine learning a...

Research hotspots and emerging trends of deep learning applications in orthopedics: A bibliometric and visualized study.

Frontiers in public health
BACKGROUND: As a research hotspot, deep learning has been continuously combined with various research fields in medicine. Recently, there is a growing amount of deep learning-based researches in orthopedics. This bibliometric analysis aimed to identi...

Identification of osteoporosis using ensemble deep learning model with panoramic radiographs and clinical covariates.

Scientific reports
Osteoporosis is becoming a global health issue due to increased life expectancy. However, it is difficult to detect in its early stages owing to a lack of discernible symptoms. Hence, screening for osteoporosis with widely used dental panoramic radio...

Deep Learning Classification of Spinal Osteoporotic Compression Fractures on Radiographs using an Adaptation of the Genant Semiquantitative Criteria.

Academic radiology
RATIONALE AND OBJECTIVES: Osteoporosis affects 9% of individuals over 50 in the United States and 200 million women globally. Spinal osteoporotic compression fractures (OCFs), an osteoporosis biomarker, are often incidental and under-reported. Accura...

An AI-based Prediction Model for Drug-drug Interactions in Osteoporosis and Paget's Diseases from SMILES.

Molecular informatics
The skeleton is one of the most important organs in the human body in assisting our motion and activities; however, bone density attenuates gradually as we age. Among common bone diseases are osteoporosis and Paget's, two of the most frequently found...

Opportunistic Osteoporosis Screening Using Chest Radiographs With Deep Learning: Development and External Validation With a Cohort Dataset.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Osteoporosis is a common, but silent disease until it is complicated by fractures that are associated with morbidity and mortality. Over the past few years, although deep learning-based disease diagnosis on chest radiographs has yielded promising res...

Applications of Machine Learning in Bone and Mineral Research.

Endocrinology and metabolism (Seoul, Korea)
In this unprecedented era of the overwhelming volume of medical data, machine learning can be a promising tool that may shed light on an individualized approach and a better understanding of the disease in the field of osteoporosis research, similar ...