Phytomedicine : international journal of phytotherapy and phytopharmacology
40037107
BACKGROUND: Resveratrol (RES), a common type of plant polyphenols, has demonstrated promising therapeutic efficacy and safety in animal models of pancreatitis and pancreatic cancer. However, a comprehensive analysis of these data is currently unavail...
Pancreatic ductal adenocarcinoma (PDAC) is recognized as one of the most lethal malignancies, characterized by late-stage diagnosis and limited therapeutic options. Risk stratification has traditionally been performed using epidemiological studies an...
Neural networks : the official journal of the International Neural Network Society
40117980
The identification of early micro-lesions and adjacent blood vessels in CT scans plays a pivotal role in the clinical diagnosis of pancreatic cancer, considering its aggressive nature and high fatality rate. Despite the widespread application of deep...
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and highly aggressive, often leading to poor patient prognosis. Existing serum biomarkers like CA19-9 are limited in early diagnosis, failing to meet clinical needs. Mac...
Pancreatic cancer is a lethal invasive tumor with one of the worst prognosis. Accurate and reliable segmentation for pancreas and pancreatic cancer on computerized tomography (CT) images is vital in clinical diagnosis and treatment. Although certain ...
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers known to humans. However, not all patients fare equally poor survival, and a minority of patients even survives advanced disease for months or years. Thus, there is a clinical ...
BACKGROUND: The cytological diagnostic process of EUS-FNA smears is time-consuming and manpower-intensive, and the conclusion could be subjective and controversial. Moreover, the relative lack of cytopathologists has limited the widespread implementa...
International journal of biological macromolecules
40086557
The high mortality rate of pancreatic cancer is closely related to its inconspicuous early symptoms and difficult diagnosis. In recent years, with the rapid development of proteomics and bioinformatics, the use of machine learning technology to analy...
This research addresses the critical challenge of early detection in pancreatic ductal adenocarcinoma (PDAC) by exploring urinary biomarkers and integrating artificial intelligence (AI) models. The study emphasizes the significance of liquid biopsy, ...
Journal of the American Medical Informatics Association : JAMIA
40056434
OBJECTIVES: Artificial intelligence (AI) models utilizing electronic health record data for disease prediction can enhance risk stratification but may lack specificity, which is crucial for reducing the economic and psychological burdens associated w...