IEEE journal of biomedical and health informatics
Sep 26, 2019
Motor fluctuations are a frequent complication in patients with Parkinson's disease (PD) where the response to medication fluctuates between ON states (medication working) and OFF states (medication has worn off). This paper describes a new data anal...
European journal of nuclear medicine and molecular imaging
Aug 31, 2019
PURPOSE: This study investigated the potential of deep convolutional neural networks (CNN) for automatic classification of FP-CIT SPECT in multi-site or multi-camera settings with variable image characteristics.
BACKGROUND: Development of valid, non-invasive biomarkers for parkinsonian syndromes is crucially needed. We aimed to assess whether non-invasive diffusion-weighted MRI can distinguish between parkinsonian syndromes using an automated imaging approac...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Aug 8, 2019
In this paper, we propose a machine learning-based virtual physical therapist (PT) system to enable personalized remote training for patients with Parkinson's disease (PD). Three physical therapy tasks with multiple difficulty levels are selected to ...
Annals of physical and rehabilitation medicine
Aug 1, 2019
BACKGROUND: Although gait disorders strongly contribute to perceived disability in people with Parkinson's disease, clinical trials have failed to identify which task-oriented gait training method can provide the best benefit. Freezing of gait remain...
Phase-amplitude cross frequency coupling (PAC) is a rather ubiquitous phenomenon that has been observed in a variety of physical domains; however, the mechanisms underlying the emergence of PAC and its functional significance in the context of neural...
Artificial intelligence, specifically machine learning, has found numerous applications in computer-aided diagnostics, monitoring and management of neurodegenerative movement disorders of parkinsonian type. These tasks are not trivial due to high int...
Journal of neuroengineering and rehabilitation
Jul 12, 2019
BACKGROUND: Clinical balance assessments often rely on functional tasks as a proxy for balance (e.g., Timed Up and Go). In contrast, analyses of balance in research settings incorporate quantitative biomechanical measurements (e.g., whole-body angula...
OBJECTIVES: To evaluate the diagnostic performance of deep learning with the convolutional neural networks (CNN) to distinguish each representative parkinsonian disorder using MRI.
BACKGROUND: Given the increasing recognition of the significance of non-motor symptoms in Parkinson's disease, we investigate the optimal use of machine learning methods for the prediction of the Montreal Cognitive Assessment (MoCA) score at year 4 f...