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Developing Noise-Resistant Three-Dimensional Single Particle Tracking Using Deep Neural Networks.

Analytical chemistry
Three-dimensional single particle tracking (3D SPT) is a powerful tool in various chemical and biological studies. In 3D SPT, z sensitive point spread functions (PSFs) are frequently used to generate different patterns, from which the axial position ...

Comparison of response surface methodology and artificial neural network to optimize novel ophthalmic flexible nano-liposomes: Characterization, evaluation, in vivo pharmacokinetics and molecular dynamics simulation.

Colloids and surfaces. B, Biointerfaces
To improve the topical delivery of pilocarpine hydrochloride (PN) to treat glaucoma, flexible nano-liposomes containing PN (PN-FLs) were prepared, optimized and characterized. Artificial neural network (ANN) and response surface methodology (RSM) wer...

Nanocomplexes composed of chitosan derivatives and β-Lactoglobulin as a carrier for anthocyanins: Preparation, stability and bioavailability in vitro.

Food research international (Ottawa, Ont.)
To improve sustained-release property, stability and bioavailability of anthocyanins (ACNs) in vitro, we fabricated the nanocomplexes with chitosan hydrochloride (CHC), carboxymethyl chitosan (CMC) and β-Lactoglobulin (β-Lg). Response surface methodo...

Convolutional neural networks automate detection for tracking of submicron-scale particles in 2D and 3D.

Proceedings of the National Academy of Sciences of the United States of America
Particle tracking is a powerful biophysical tool that requires conversion of large video files into position time series, i.e., traces of the species of interest for data analysis. Current tracking methods, based on a limited set of input parameters ...

Evaluation of machine learning techniques with multiple remote sensing datasets in estimating monthly concentrations of ground-level PM.

Environmental pollution (Barking, Essex : 1987)
Fine particulate matter (PM) has been recognized as a key air pollutant that can influence population health risk, especially during extreme cases such as wildfires. Previous studies have applied geospatial techniques such as land use regression to m...

Aligned Carbon Nanotube Synaptic Transistors for Large-Scale Neuromorphic Computing.

ACS nano
This paper presents aligned carbon nanotube (CNT) synaptic transistors for large-scale neuromorphic computing systems. The synaptic behavior of these devices is achieved via charge-trapping effects, commonly observed in carbon-based nanoelectronics. ...

Recognition Tunneling of Canonical and Modified RNA Nucleotides for Their Identification with the Aid of Machine Learning.

ACS nano
In the present study, we demonstrate a tunneling nanogap technique to identify individual RNA nucleotides, which can be used as a mechanism to read the nucleobases for direct sequencing of RNA in a solid-state nanopore. The tunneling nanogap is compo...

A Robot Equipped with a High-Speed LSPR Gas Sensor Module for Collecting Spatial Odor Information from On-Ground Invisible Odor Sources.

ACS sensors
Improving the efficiency of detecting the spatial distribution of gas information with a mobile robot is a great challenge that requires rapid sample collection, which is basically determined by the speed of operation of gas sensors. The present work...

The label-free immunosensor based on rhodium@palladium nanodendrites/sulfo group functionalized multi-walled carbon nanotubes for the sensitive analysis of carcino embryonic antigen.

Analytica chimica acta
In this work, bimetallic core-shell rhodium@palladium nanodendrites (Rh@Pd NDs) loaded on sulfo group functionalized multi-walled carbon nanotubes (MWCNTs-SOH) were combined to form Rh@Pd NDs/MWCNTs-SOH nanocomposites. And the composites were used to...

Simultaneous determination of 11 phthalate esters in bottled beverages by graphene oxide coated hollow fiber membrane extraction coupled with supercritical fluid chromatography.

Analytica chimica acta
Phthalate esters (PAEs) are a group of serious environmental pollutants, which lead to carcinogenicity or tumorigenicity in human body. In this study, a rapid, sensitive and green method by graphene oxide coated hollow fiber membrane extraction (GO-H...