AIMC Topic: Pharmacokinetics

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Challenges and Opportunities for Increasing the Knowledge Base Related to Drug Biotransformation and Pharmacokinetics during Growth and Development.

Drug metabolism and disposition: the biological fate of chemicals Jul 1, 2016
It is generally acknowledged that there is a need and role for informative pharmacokinetic models to improve predictions and simulation as well as individualization of drug therapy in pediatric populations of different ages and developmental stages. ...
Humans Computer Simulation Infant, Newborn Aging Infant Adolescent Child, Preschool Child Age Factors Pharmaceutical Preparations Models, Biological Knowledge Bases Biotransformation Pharmacokinetics Membrane Transport Proteins Gene Expression Regulation, Enzymologic Child Development Enzymes Gene Expression Regulation, Developmental Adolescent Development
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