AIMC Topic: Phenotype

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Machine learning in photosynthesis: Prospects on sustainable crop development.

Plant science : an international journal of experimental plant biology Jul 18, 2023
Improving photosynthesis is a promising avenue to increase food security. Studying photosynthetic traits with the aim to improve efficiency has been one of many strategies to increase crop yield but analyzing large data sets presents an ongoing chall...
Phenotype Photosynthesis Machine Learning
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Stratification of diabetes in the context of comorbidities, using representation learning and topological data analysis.

Scientific reports Jul 16, 2023
Diabetes is a heterogenous, multimorbid disorder with a large variation in manifestations, trajectories, and outcomes. The aim of this study is to validate a novel machine learning method for the phenotyping of diabetes in the context of comorbiditie...
Aged Male Phenotype Female Risk Assessment Comorbidity Cardiovascular Diseases Middle Aged Humans Data Analysis Kidney Diseases Diabetes Mellitus Unsupervised Machine Learning
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Intermediately synchronised brain states optimise trade-off between subject specificity and predictive capacity.

Communications biology Jul 10, 2023
Functional connectivity (FC) refers to the statistical dependencies between activity of distinct brain areas. To study temporal fluctuations in FC within the duration of a functional magnetic resonance imaging (fMRI) scanning session, researchers hav...
Research Personnel Machine Learning Phenotype Humans Brain Time Factors
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Cancer immunotherapy response prediction from multi-modal clinical and image data using semi-supervised deep learning.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology Jul 4, 2023
BACKGROUND AND PURPOSE: Immunotherapy is a standard treatment for many tumor types. However, only a small proportion of patients derive clinical benefit and reliable predictive biomarkers of immunotherapy response are lacking. Although deep learning ...
Phenotype Retrospective Studies ROC Curve Humans Immunotherapy Stomach Neoplasms Deep Learning
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One hundred important questions facing plant science derived using a large language model.

Trends in plant science Jun 30, 2023
Artificial intelligence (AI) is advancing rapidly and continually evolving in various fields. Recently, the release of ChatGPT has sparked significant public interest. In this study, we revisit the '100 Important Questions Facing Plant Science' by le...
Language Artificial Intelligence Phenotype
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DeepCGP: A Deep Learning Method to Compress Genome-Wide Polymorphisms for Predicting Phenotype of Rice.

IEEE/ACM transactions on computational biology and bioinformatics Jun 5, 2023
Genomic selection (GS) is expected to accelerate plant and animal breeding. During the last decade, genome-wide polymorphism data have increased, which has raised concerns about storage cost and computational time. Several individual studies have att...
Phenotype Genotype Genomics Bayes Theorem Models, Genetic Polymorphism, Single Nucleotide Animals Oryza Deep Learning
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Echo2Pheno: a deep-learning application to uncover echocardiographic phenotypes in conscious mice.

Mammalian genome : official journal of the International Mammalian Genome Society May 23, 2023
Echocardiography, a rapid and cost-effective imaging technique, assesses cardiac function and structure. Despite its popularity in cardiovascular medicine and clinical research, image-derived phenotypic measurements are manually performed, requiring ...
Mice Heart Algorithms Echocardiography Phenotype Deep Learning Animals Ribonucleases
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FooDis: A food-disease relation mining pipeline.

Artificial intelligence in medicine May 20, 2023
Nowadays, it is really important and crucial to follow the new biomedical knowledge that is presented in scientific literature. To this end, Information Extraction pipelines can help to automatically extract meaningful relations from textual data tha...
Information Storage and Retrieval Databases, Factual Phenotype Natural Language Processing
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Prediction of Kv11.1 potassium channel PAS-domain variants trafficking via machine learning.

Journal of molecular and cellular cardiology May 13, 2023
Congenital long QT syndrome (LQTS) is characterized by a prolonged QT-interval on an electrocardiogram (ECG). An abnormal prolongation in the QT-interval increases the risk for fatal arrhythmias. Genetic variants in several different cardiac ion chan...
KCNQ1 Potassium Channel Long QT Syndrome Mutation, Missense Machine Learning Phenotype Humans
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Rapid and Accurate Identification of Cell Phenotypes of Different Drug Mechanisms by Using Single-Cell Fluorescence Images Via Deep Learning.

Analytical chemistry May 10, 2023
Identification of a drug mechanism is vital for drug development. However, it often resorts to the expensive and cumbersome omics methods along with complex data analysis. Herein, we developed a methodology to analyze organelle staining images of sin...
Phenotype Fluorescence Deep Learning Algorithms
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