AIMC Topic: Phosphorylation

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Rapid Communication: Prolactin and hydrocortisone impact TNFα-mediated mitogen-activated protein kinase signaling and inflammation of bovine mammary epithelial (MAC-T) cells.

Journal of animal science Dec 1, 2017
The objective of this study was to evaluate the effects of the hormones prolactin (PRL) and hydrocortisone (HC) on bovine mammary alveolar (MAC-T) cells mitogen-activated protein kinase (MAPK) inflammatory signaling and inflammatory gene expression. ...
Mammary Glands, Animal JNK Mitogen-Activated Protein Kinases Anti-Inflammatory Agents Mitogen-Activated Protein Kinases Alveolar Epithelial Cells Inflammation Hydrocortisone Signal Transduction Prolactin Phosphorylation Tumor Necrosis Factor-alpha Cells, Cultured Female Animals Cattle
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[Y-27632 protects H9c2 cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy pathway].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology Nov 1, 2017
Objective To investigate the protective effect of preconditioning with Rho-kinase inhibitor Y-27632 on H9c2 cardiomyocytes against hypoxia/reoxygenation (H/R) injury, and explore its underlying mechanism. Methods H9c2 cardiomyocytes were divided into...
Myocytes, Cardiac Beclin-1 L-Lactate Dehydrogenase Cell Hypoxia Myosin Light Chains Phosphorylation Oxygen Autophagy Pyridines Amides Cell Line Cell Survival Animals Rats Protective Agents Signal Transduction Apoptosis
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iMulti-HumPhos: a multi-label classifier for identifying human phosphorylated proteins using multiple kernel learning based support vector machines.

Molecular bioSystems Jul 25, 2017
Protein phosphorylation plays a potential role in regulating protein conformation and functions. As a result, identifying an uncharacterized protein sequence as a phosphorylated protein is a very meaningful problem and an urgent issue for both basic ...
Protein Processing, Post-Translational Proteins Phosphorylation Software Computational Biology Support Vector Machine Humans Internet Tyrosine Benchmarking Serine Datasets as Topic Threonine
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[Effect of glutaredoxin on oxidative stress of umbilical vein endothelial cell exposed to Porphyromonas gingivalis lipo- polysaccharide].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology Dec 1, 2015
OBJECTIVE: This study measures the glutaredoxin (Grx) gene and protein expression in umbilical vein endothelial cells upon exposure to Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS). The involvement of the Akt-signaling pathway is ...
Humans Proto-Oncogene Proteins c-akt Endothelial Cells Umbilical Veins Glutaredoxins Lipopolysaccharides Phosphorylation Porphyromonas gingivalis Oxidative Stress Signal Transduction
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[Effects of exogenous recombinant human basic fibroblast growth factor on the healing of muscles in rats after deep tissue injury of pressure ulcers].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns Dec 1, 2015
OBJECTIVE: To investigate the effect of exogenous recombinant human basic fibroblast growth factor (rhbFGF) on the healing of muscles in rats after deep tissue injury of pressure ulcers.
Pressure Ulcer Disease Models, Animal Signal Transduction Phosphorylation TOR Serine-Threonine Kinases Humans Recombinant Proteins Rats, Sprague-Dawley Proto-Oncogene Proteins c-akt Fibroblast Growth Factor 2 Animals Wound Healing Rats Myogenin
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[Qinghuachang Decoction Inhibited NF-kappaB Activation in LPS-induced Human Enterocytes].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine Nov 1, 2015
OBJECTIVE: To explore anti-inflammation and mechanism of Qinghuachang Decoction (QD) by using LPS stimulated differentiated colon cancer Caco-2 cells (as an inflammation model of human enterocytes).
Tumor Necrosis Factor-alpha Colon Inflammation Humans Interleukin-8 Drugs, Chinese Herbal NF-kappa B Lipopolysaccharides Caco-2 Cells Phosphorylation I-kappa B Proteins NF-KappaB Inhibitor alpha Enterocytes
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RLIMS-P 2.0: A Generalizable Rule-Based Information Extraction System for Literature Mining of Protein Phosphorylation Information.

IEEE/ACM transactions on computational biology and bioinformatics Jan 1, 2015
We introduce RLIMS-P version 2.0, an enhanced rule-based information extraction (IE) system for mining kinase, substrate, and phosphorylation site information from scientific literature. Consisting of natural language processing and IE modules, the s...
Databases, Protein Phosphorylation Natural Language Processing Phosphoproteins Data Mining Software Computational Biology
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