AIMC Topic: Precision Medicine

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Artificial Intelligence in Bulk and Single-Cell RNA-Sequencing Data to Foster Precision Oncology.

International journal of molecular sciences
Artificial intelligence, or the discipline of developing computational algorithms able to perform tasks that requires human intelligence, offers the opportunity to improve our idea and delivery of precision medicine. Here, we provide an overview of a...

Artificial intelligence in oncology: From bench to clinic.

Seminars in cancer biology
In the past few years, Artificial Intelligence (AI) techniques have been applied to almost every facet of oncology, from basic research to drug development and clinical care. In the clinical arena where AI has perhaps received the most attention, AI ...

Explainable artificial intelligence in high-throughput drug repositioning for subgroup stratifications with interventionable potential.

Journal of biomedical informatics
Enabling precision medicine requires developing robust patient stratification methods as well as drugs tailored to homogeneous subgroups of patients from a heterogeneous population. Developing de novo drugs is expensive and time consuming with an ult...

Challenges and opportunities for artificial intelligence in oncological imaging.

Clinical radiology
Imaging plays a key role in oncology, including the diagnosis and detection of cancer, determining clinical management, assessing treatment response, and complications of treatment or disease. The current use of clinical oncology is predominantly qua...

Towards the Interpretability of Machine Learning Predictions for Medical Applications Targeting Personalised Therapies: A Cancer Case Survey.

International journal of molecular sciences
Artificial Intelligence is providing astonishing results, with medicine being one of its favourite playgrounds. Machine Learning and, in particular, Deep Neural Networks are behind this revolution. Among the most challenging targets of interest in me...

Digital Transformation in Personalized Medicine with Artificial Intelligence and the Internet of Medical Things.

Omics : a journal of integrative biology
Digital transformation is impacting every facet of science and society, not least because there is a growing need for digital services and products with the COVID-19 pandemic. But the need for digital transformation in diagnostics and personalized me...

Three ways of knowing: the integration of clinical expertise, evidence-based medicine, and artificial intelligence in assisted reproductive technologies.

Journal of assisted reproduction and genetics
Decision-making in fertility care is on the cusp of a significant frameshift. Online tools to integrate artificial intelligence into the decision-making process across all aspects of ART are rapidly emerging. These tools have the potential to improve...

Current Status and Quality of Machine Learning-Based Radiomics Studies for Glioma Grading: A Systematic Review.

Oncology
INTRODUCTION: Radiomics now has significant momentum in the era of precision medicine. Glioma is one of the pathologies that has been extensively evaluated by radiomics. However, this technique has not been incorporated into clinical practice. In thi...

Deep learning assisted multi-omics integration for survival and drug-response prediction in breast cancer.

BMC genomics
BACKGROUND: Survival and drug response are two highly emphasized clinical outcomes in cancer research that directs the prognosis of a cancer patient. Here, we have proposed a late multi omics integrative framework that robustly quantifies survival an...

Artificial Intelligence-Aided Precision Medicine for COVID-19: Strategic Areas of Research and Development.

Journal of medical Internet research
Artificial intelligence (AI) technologies can play a key role in preventing, detecting, and monitoring epidemics. In this paper, we provide an overview of the recently published literature on the COVID-19 pandemic in four strategic areas: (1) triage,...