Specialized brain structures encode spatial locations and movements, yet there is growing evidence that this information is also represented in the rodent medial prefrontal cortex (mPFC). Disambiguating such information from the encoding of other typ...
Motor deficits are common outcomes of neurological conditions such as stroke. In order to design personalised motor rehabilitation programmes such as robot-assisted therapy, it would be advantageous to predict how a patient might respond to such trea...
Reinforcement learning has been widely used in explaining animal behavior. In reinforcement learning, the agent learns the value of the states in the task, collectively constituting the task state space, and uses the knowledge to choose actions and a...
BMC medical informatics and decision making
Dec 20, 2017
BACKGROUND: Schizophrenia is a kind of serious mental illness. Due to the lack of an objective physiological data supporting and a unified data analysis method, doctors can only rely on the subjective experience of the data to distinguish normal peop...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nov 7, 2017
Working memory (WM) and decision-making (DM) are fundamental cognitive functions involving a distributed interacting network of brain areas, with the posterior parietal cortex (PPC) and prefrontal cortex (PFC) at the core. However, the shared and dis...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Oct 6, 2017
Complex cognitive behaviors, such as context-switching and rule-following, are thought to be supported by the prefrontal cortex (PFC). Neural activity in the PFC must thus be specialized to specific tasks while retaining flexibility. Nonlinear "mixed...
Difficulty regulating positive mood and energy is a feature that cuts across different pediatric psychiatric disorders. Yet, little is known regarding the neural mechanisms underlying different developmental trajectories of positive mood and energy r...
Neural networks : the official journal of the International Neural Network Society
Mar 22, 2017
Persistent irregular activity is defined as elevated irregular neural discharges in the brain in such a way that while the average network activity displays high frequency oscillations, the participating neurons display irregular and low frequency os...
A neural synchrony model of cognitive control is proposed. It construes cognitive control as a higher-level action to synchronize lower-level brain areas. Here, a controller prefrontal area (medial frontal cortex) can synchronize two cortical process...
Proceedings of the National Academy of Sciences of the United States of America
Dec 12, 2016
The effectiveness of today's human-machine interaction is limited by a communication bottleneck as operators are required to translate high-level concepts into a machine-mandated sequence of instructions. In contrast, we demonstrate effective, goal-o...
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