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Radiotherapy, Intensity-Modulated

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Deep learning-enabled EPID-based 3D dosimetry for dose verification of step-and-shoot radiotherapy.

Medical physics
PURPOSE: The study aims at a novel dosimetry methodology to reconstruct a 3D dose distribution as imparted to a virtual cylindrical phantom using an electronic portal imaging device (EPID).

Deep learning method for prediction of patient-specific dose distribution in breast cancer.

Radiation oncology (London, England)
BACKGROUND: Patient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction model was developed for a left-...

Managing tumor changes during radiotherapy using a deep learning model.

Medical physics
PURPOSE: We propose a treatment planning framework that accounts for weekly lung tumor shrinkage using cone beam computed tomography (CBCT) images with a deep learning-based model.

Applications of machine and deep learning to patient-specific IMRT/VMAT quality assurance.

Journal of applied clinical medical physics
In order to deliver accurate and safe treatment to cancer patients in radiation therapy using advanced techniques such as intensity modulated radiation therapy (IMRT) and volumetric-arc radiation therapy (VMAT), patient specific quality assurance (QA...

Development of in-house fully residual deep convolutional neural network-based segmentation software for the male pelvic CT.

Radiation oncology (London, England)
BACKGROUND: This study aimed to (1) develop a fully residual deep convolutional neural network (CNN)-based segmentation software for computed tomography image segmentation of the male pelvic region and (2) demonstrate its efficiency in the male pelvi...

A feasibility study on deep learning-based individualized 3D dose distribution prediction.

Medical physics
PURPOSE: Radiation therapy treatment planning is a trial-and-error, often time-consuming process. An approximately optimal dose distribution corresponding to a specific patient's anatomy can be predicted by using pre-trained deep learning (DL) models...

Interobserver variability in organ at risk delineation in head and neck cancer.

Radiation oncology (London, England)
BACKGROUND: In radiotherapy inaccuracy in organ at risk (OAR) delineation can impact treatment plan optimisation and treatment plan evaluation. Brouwer et al. showed significant interobserver variability (IOV) in OAR delineation in head and neck canc...

A hierarchical deep reinforcement learning framework for intelligent automatic treatment planning of prostate cancer intensity modulated radiation therapy.

Physics in medicine and biology
We have previously proposed an intelligent automatic treatment planning (IATP) framework that builds a virtual treatment planner network (VTPN) to operate a treatment planning system (TPS) to generate high-quality radiation therapy (RT) treatment pla...

Technical Note: Dose prediction for head and neck radiotherapy using a three-dimensional dense dilated U-net architecture.

Medical physics
PURPOSE: Radiation therapy treatment planning is a time-consuming and iterative manual process. Consequently, plan quality varies greatly between and within institutions. Artificial intelligence shows great promise in improving plan quality and reduc...