AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Proton spot dose estimation based on positron activity distributions with neural network.

Medical physics
BACKGROUND: Positron emission tomography (PET) has been investigated for its ability to reconstruct proton-induced positron activity distributions in proton therapy. This technique holds potential for range verification in clinical practice. Recently...

Synthetic CT generation for pelvic cases based on deep learning in multi-center datasets.

Radiation oncology (London, England)
BACKGROUND AND PURPOSE: To investigate the feasibility of synthesizing computed tomography (CT) images from magnetic resonance (MR) images in multi-center datasets using generative adversarial networks (GANs) for rectal cancer MR-only radiotherapy.

Localized fine-tuning and clinical evaluation of deep-learning based auto-segmentation (DLAS) model for clinical target volume (CTV) and organs-at-risk (OAR) in rectal cancer radiotherapy.

Radiation oncology (London, England)
BACKGROUND AND PURPOSE: Various deep learning auto-segmentation (DLAS) models have been proposed, some of which have been commercialized. However, the issue of performance degradation is notable when pretrained models are deployed in the clinic. This...

Artificial intelligence in radiotherapy: Current applications and future trends.

Diagnostic and interventional imaging
Radiation therapy has dramatically changed with the advent of computed tomography and intensity modulation. This added complexity to the workflow but allowed for more precise and reproducible treatment. As a result, these advances required the accura...

From plan to delivery: Machine learning based positional accuracy prediction of multi-leaf collimator and estimation of delivery effect in volumetric modulated arc therapy.

Journal of applied clinical medical physics
PURPOSE: The positional accuracy of MLC is an important element in establishing the exact dosimetry in VMAT. We comprehensively analyzed factors that may affect MLC positional accuracy in VMAT, and constructed a model to predict MLC positional deviat...

Comparison of the use of a clinically implemented deep learning segmentation model with the simulated study setting for breast cancer patients receiving radiotherapy.

Acta oncologica (Stockholm, Sweden)
BACKGROUND: Deep learning (DL) models for auto-segmentation in radiotherapy have been extensively studied in retrospective and pilot settings. However, these studies might not reflect the clinical setting. This study compares the use of a clinically ...

Challenges and opportunities in the development and clinical implementation of artificial intelligence based synthetic computed tomography for magnetic resonance only radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) can serve as a substitute for planning CT in radiation therapy (RT), thereby removing registration uncertainties associated with multi-modality imaging pairing, reduc...

The Evolving Role of Artificial Intelligence in Radiotherapy Treatment Planning-A Literature Review.

Clinical oncology (Royal College of Radiologists (Great Britain))
This paper examines the integration of artificial intelligence (AI) in radiotherapy for cancer treatment. The importance of radiotherapy in cancer management and its time-intensive planning process make AI adoption appealing especially with the escal...

Re-evaluation of the prospective risk analysis for artificial-intelligence driven cone beam computed tomography-based online adaptive radiotherapy after one year of clinical experience.

Zeitschrift fur medizinische Physik
Cone-beam computed tomography (CBCT)-based online adaptation is increasingly being introduced into many clinics. Upon implementation of a new treatment technique, a prospective risk analysis is required and enhances workflow safety. We conducted a ri...

Deep learning promoted target volumes delineation of total marrow and total lymphoid irradiation for accelerated radiotherapy: A multi-institutional study.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
BACKGROUND AND PURPOSE: One of the current roadblocks to the widespread use of Total Marrow Irradiation (TMI) and Total Marrow and Lymphoid Irradiation (TMLI) is the challenging difficulties in tumor target contouring workflow. This study aims to dev...