Journal of applied clinical medical physics
Sep 1, 2025
BACKGROUND: In contemporary radiation therapy, the radiation is modulated to conform the prescription dose to the tumor and spare organs at risk. The modulation results from a complex mathematical calculation that requires several iterations to reach...
BACKGROUND: Radiotherapy treatment planning is a time-consuming task that requires expert and skilled manpower, particularly for weight adjustment. Valuable attempts have been made to automate the treatment planning process as well as decrease comput...
BACKGROUND: Patient-specific quality assurance (PSQA) is essential to guarantee the requested accuracy and safety of high-precision radiotherapy treatments. With the widespread adoption of modulated-intensity techniques, there is a growing need for i...
BACKGROUND: Knowledge-based planning (KBP) is a data-driven approach that utilizes the knowledge from previous high-quality treatment plans to predict dose-volume histogram (DVH) parameters for organs-at-risk (OARs) in new cases. Research has demonst...
Journal of applied clinical medical physics
Sep 1, 2025
BACKGROUND: Deep learning (DL)-based organ segmentation is increasingly used in radiotherapy. While methods exist to generate voxel-wise uncertainty maps from DL-based auto-segmentation models, these maps are rarely presented to clinicians.
Journal of applied clinical medical physics
Sep 1, 2025
OBJECTIVE: Measurement-based patient specific quality assurance (PSQA) is an increasingly debated topic among medical physicists. Developments like online adaptive radiotherapy and same-day stereotactic treatments limit the time to do measurement-bas...
Journal of applied clinical medical physics
Sep 1, 2025
BACKGROUND: In external beam radiation therapy (EBRT) for prostate cancer, both MRI and CT are typically used-CT provides electron density for dose calculation and visualization of bony anatomy and fiducial markers, while MRI offers superior soft tis...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Aug 1, 2025
BACKGROUND AND PURPOSE: Synthetic CT (sCT) generation from cone-beam CT (CBCT) must maintain stable performance and allow for accurate dose calculation across all treatment fractions to effectively support adaptive proton therapy. This study evaluate...
Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One such approach is to use two independent auto-contouring models and compare them geometrically for acceptability. This is not effective because g...
International journal of radiation oncology, biology, physics
Jul 15, 2025
Dramatic strides have been made in real-time adaptive radiation therapy, where treating single tumors as dynamic but rigid bodies has demonstrated a halving of toxicities for prostate cancer. However, the human body is much more complex than a rigid ...
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