AIMC Topic: Ranibizumab

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Machine Learning Can Predict Anti-VEGF Treatment Demand in a Treat-and-Extend Regimen for Patients with Neovascular AMD, DME, and RVO Associated Macular Edema.

Ophthalmology. Retina May 8, 2021
PURPOSE: To assess the potential of machine learning to predict low and high treatment demand in real life in patients with neovascular age-related macular degeneration (nAMD), retinal vein occlusion (RVO), and diabetic macular edema (DME) treated ac...
Retinal Vein Occlusion Aged, 80 and over Male Middle Aged Angiogenesis Inhibitors Follow-Up Studies Machine Learning Macular Edema Prognosis Humans Vascular Endothelial Growth Factor A Retrospective Studies Diabetic Retinopathy Intravitreal Injections Female Ranibizumab Aged Wet Macular Degeneration
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Subfoveal choroidal thickness changes after intravitreal ranibizumab injections in different patterns of diabetic macular edema using a deep learning-based auto-segmentation.

International ophthalmology Mar 30, 2021
PURPOSE: To evaluate the effect of intravitreal injection of ranibizumab (IVR) on subfoveal choroidal thickness (SFCT) and its relationship with central macular thickness (CMT) and best-corrected visual acuity (BCVA) changes in eyes with center-invol...
Angiogenesis Inhibitors Diabetes Mellitus Choroid Tomography, Optical Coherence Macular Edema Humans Diabetic Retinopathy Prospective Studies Retrospective Studies Deep Learning Intravitreal Injections Ranibizumab Retinal Detachment
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Predicting Incremental and Future Visual Change in Neovascular Age-Related Macular Degeneration Using Deep Learning.

Ophthalmology. Retina Jan 28, 2021
PURPOSE: To evaluate the predictive usefulness of quantitative imaging biomarkers, acquired automatically from OCT scans, of cross-sectional and future visual outcomes of patients with neovascular age-related macular degeneration (AMD) starting anti-...
Humans Prognosis Visual Acuity Tomography, Optical Coherence Vascular Endothelial Growth Factor A Intravitreal Injections Ranibizumab Wet Macular Degeneration Male Middle Aged Deep Learning Angiogenesis Inhibitors Follow-Up Studies Retrospective Studies Female Aged Aged, 80 and over Cross-Sectional Studies
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Quantification of Key Retinal Features in Early and Late Age-Related Macular Degeneration Using Deep Learning.

American journal of ophthalmology Jan 8, 2021
PURPOSE: We sought to develop and validate a deep learning model for segmentation of 13 features associated with neovascular and atrophic age-related macular degeneration (AMD).
Vascular Endothelial Growth Factor A Intravitreal Injections Humans Recombinant Fusion Proteins Neural Networks, Computer Ranibizumab Female Wet Macular Degeneration Aged Receptors, Vascular Endothelial Growth Factor Retinal Drusen Choroidal Neovascularization Geographic Atrophy ROC Curve Angiogenesis Inhibitors Models, Statistical Visual Acuity Tomography, Optical Coherence Aged, 80 and over Sensitivity and Specificity Male Middle Aged Deep Learning
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Impact of macular fluid volume fluctuations on visual acuity during anti-VEGF therapy in eyes with nAMD.

Eye (London, England) Jan 7, 2021
OBJECTIVES: To study the effect of repeated retinal thickness fluctuations during the anti-VEGF therapy maintenance phase in neovascular age-related macular degeneration (nAMD).
Intravitreal Injections Ranibizumab Wet Macular Degeneration Bevacizumab Subretinal Fluid Artificial Intelligence Angiogenesis Inhibitors Treatment Outcome Visual Acuity Tomography, Optical Coherence Humans
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Prediction of visual outcomes by an artificial neural network following intravitreal injection and laser therapy for retinopathy of prematurity.

The British journal of ophthalmology Nov 19, 2019
AIMS: To construct a program to predict the visual acuity (VA), best corrected VA (BCVA) and spherical equivalent (SE) of patients with retinopathy of prematurity (ROP) from 3 to 12 years old after intravitreal injection (IVI) of anti-vascular endoth...
Visual Acuity Predictive Value of Tests Vascular Endothelial Growth Factor A Intravitreal Injections Ranibizumab Retinopathy of Prematurity Bevacizumab Laser Coagulation Male Refraction, Ocular Child, Preschool Child Angiogenesis Inhibitors Humans Neural Networks, Computer Retrospective Studies Female
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[Chances of Artificial Intelligence and Big Data for the Diagnosis and Treatment of Age-related Macular Degeneration].

Klinische Monatsblatter fur Augenheilkunde Oct 31, 2019
Age-related macular degeneration (AMD) is the leading cause of blindness in the western world. Intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) is an effective therapy of the neovascular form of this condition. Multimodal...
Choroidal Neovascularization Angiogenesis Inhibitors Vascular Endothelial Growth Factor A Macular Degeneration Intravitreal Injections Ranibizumab Humans Artificial Intelligence Big Data
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Automated diagnosis and quantitative analysis of plus disease in retinopathy of prematurity based on deep convolutional neural networks.

Acta ophthalmologica Sep 27, 2019
BACKGROUND: The purpose of this study was to develop an automated diagnosis and quantitative analysis system for plus disease. The system provides a diagnostic decision but also performs quantitative analysis of the typical pathological features of t...
Image Interpretation, Computer-Assisted Infant, Premature Intravitreal Injections Ranibizumab Retinopathy of Prematurity Infant, Newborn Diagnosis, Computer-Assisted Deep Learning ROC Curve Angiogenesis Inhibitors Retinal Vessels Humans Infant, Extremely Low Birth Weight
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Machine Learning to Analyze the Prognostic Value of Current Imaging Biomarkers in Neovascular Age-Related Macular Degeneration.

Ophthalmology. Retina May 31, 2017
PURPOSE: To evaluate the potential of machine learning to predict best-corrected visual acuity (BCVA) outcomes from structural and functional assessments during the initiation phase in patients receiving standardized ranibizumab therapy for neovascul...
Tomography, Optical Coherence Fundus Oculi Humans Macula Lutea Reproducibility of Results Vascular Endothelial Growth Factor A Ranibizumab Machine Learning Angiogenesis Inhibitors Intravitreal Injections Retinal Pigment Epithelium Prospective Studies Treatment Outcome Fluorescein Angiography Wet Macular Degeneration Prognosis Follow-Up Studies Visual Acuity
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GENERATIVE DEEP LEARNING APPROACH TO PREDICT POSTTREATMENT OPTICAL COHERENCE TOMOGRAPHY IMAGES OF AGE-RELATED MACULAR DEGENERATION AFTER 12 MONTHS.

Retina (Philadelphia, Pa.) Jun 1, 2025
PURPOSE: Predicting long-term anatomical responses in neovascular age-related macular degeneration patients is critical for patient-specific management. This study validates a generative deep learning model to predict 12-month posttreatment optical c...
Aged, 80 and over Male Deep Learning Time Factors Angiogenesis Inhibitors Humans Retrospective Studies Female Aged Intravitreal Injections Fluorescein Angiography Follow-Up Studies Macula Lutea Ranibizumab Visual Acuity Wet Macular Degeneration Tomography, Optical Coherence Fundus Oculi Vascular Endothelial Growth Factor A
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