AIMC Topic: Rats

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Deep-Learning-Based Algorithm for the Removal of Electromagnetic Interference Noise in Photoacoustic Endoscopic Image Processing.

Sensors (Basel, Switzerland)
Despite all the expectations for photoacoustic endoscopy (PAE), there are still several technical issues that must be resolved before the technique can be successfully translated into clinics. Among these, electromagnetic interference (EMI) noise, in...

Estimating muscle activation from EMG using deep learning-based dynamical systems models.

Journal of neural engineering
. To study the neural control of movement, it is often necessary to estimate how muscles are activated across a variety of behavioral conditions. One approach is to try extracting the underlying neural command signal to muscles by applying latent var...

Prediction of In Vivo Pharmacokinetic Parameters and Time-Exposure Curves in Rats Using Machine Learning from the Chemical Structure.

Molecular pharmaceutics
Animal pharmacokinetic (PK) data as well as human and animal in vitro systems are utilized in drug discovery to define the rate and route of drug elimination. Accurate prediction and mechanistic understanding of drug clearance and disposition in anim...

Rapid, automated nerve histomorphometry through open-source artificial intelligence.

Scientific reports
We aimed to develop and validate a deep learning model for automated segmentation and histomorphometry of myelinated peripheral nerve fibers from light microscopic images. A convolutional neural network integrated in the AxonDeepSeg framework was tra...

A behavioral paradigm for cortical control of a robotic actuator by freely moving rats in a one-dimensional two-target reaching task.

Journal of neuroscience methods
BACKGROUND: Controlling the trajectory of a neuroprosthesis to reach distant targets is a commonly used brain-machine interface (BMI) task in primates and has not been available for rodents yet.

Hepatic enzymes and immunoinflammatory response to Bio-C Temp bioceramic intracanal medication implanted into the subcutaneous tissue of rats.

Scientific reports
Our purpose was to evaluate the biocompatibility and hepatotoxicity of a new bioceramic intracanal medicament, Bio-C Temp (BIO). The biological properties of BIO were compared with calcium hydroxide-based intracanal medicament (Calen; CAL), used as g...

Production of Bioactive Substances to Alleviates Hangover and Ethanol-Induced Liver Damage through Fermentation of Using .

Molecules (Basel, Switzerland)
The purpose of this study is to evaluate the effect of the bioconversion products of extract fermented by (OEFL) on relieving hangovers and improving liver function. In addition, the bioactive substance of the OEFL, which alleviates hangover and et...

Ultrafast water-fat separation using deep learning-based single-shot MRI.

Magnetic resonance in medicine
PURPOSE: To present a deep learning-based reconstruction method for spatiotemporally encoded single-shot MRI to simultaneously obtain water and fat images.

Disease-Specific Imaging Utilizing Support Vector Machine Classification of H-Scan Parameters: Assessment of Steatosis in a Rat Model.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control
In medical imaging, quantitative measurements have shown promise in identifying diseases by classifying normal versus pathological parameters from tissues. The support vector machine (SVM) has shown promise as a supervised classification algorithm an...

High-throughput segmentation of unmyelinated axons by deep learning.

Scientific reports
Axonal characterizations of connectomes in healthy and disease phenotypes are surprisingly incomplete and biased because unmyelinated axons, the most prevalent type of fibers in the nervous system, have largely been ignored as their quantitative asse...