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Renal Insufficiency, Chronic

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Effect of Ramadan Fasting on Chronic Inflammation and Body Composition in Patients with Chronic Kidney Disease.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Chronic kidney disease (CKD) is associated with a state of chronic inflammation which is responsible for many of the pathophysiological changes detected in these patients. Many studies have evaluated the effect of Ramadan fasting on renal function an...

Mantis-ml: Disease-Agnostic Gene Prioritization from High-Throughput Genomic Screens by Stochastic Semi-supervised Learning.

American journal of human genetics
Access to large-scale genomics datasets has increased the utility of hypothesis-free genome-wide analyses. However, gene signals are often insufficiently powered to reach experiment-wide significance, triggering a process of laborious triaging of gen...

Artificial intelligence approaches to improve kidney care.

Nature reviews. Nephrology
Artificial intelligence is increasingly being used to improve diagnosis and prognostication for acute and chronic kidney diseases. Studies published in 2019 relied on a variety of available data sources towards this objective, including electronic he...

Prediction of Clinical Events in Hemodialysis Patients Using an Artificial Neural Network.

Studies in health technology and informatics
Advanced chronic kidney disease (CKD) requires routine renal replacement therapy (RRT) that involves hemodialysis (HD) which may cause increased risk of muscle spasms, cardiovascular events, and death. We used Artificial Neural Network (ANN) method t...

Development and Validation of a Deep-Learning Model to Screen for Hyperkalemia From the Electrocardiogram.

JAMA cardiology
IMPORTANCE: For patients with chronic kidney disease (CKD), hyperkalemia is common, associated with fatal arrhythmias, and often asymptomatic, while guideline-directed monitoring of serum potassium is underused. A deep-learning model that enables non...

Modulation of aldosterone levels by aldosterone synthase promoter polymorphism and association with eGFR decline in patients with chronic kidney disease.

Discovery medicine
To determine whether -344T/C CYP11B2 promoter polymorphism affects serum aldosterone levels and whether this polymorphism is an indicator of eGFR decline in patients with chronic kidney disease. -344 C/T CYP11B2 gene polymorphism analysis was perform...

Chronic Kidney Disease: Detection and Evaluation.

American family physician
Chronic kidney disease affects 47 million people in the United States and is associated with significant health care costs, morbidity, and mortality. Because this disease can silently progress to advanced stages, early detection is critical for initi...