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Automated heart sound classification system from unsegmented phonocardiogram (PCG) using deep neural network.

Physical and engineering sciences in medicine
Given the patient to doctor ratio of 50,000:1 in low income and middle-income countries, there is a need for automated heart sound classification system that can screen the Phonocardiogram (PCG) records in real-time. This paper proposes deep neural n...

Machine learning algorithm to predict mortality in patients undergoing continuous renal replacement therapy.

Critical care (London, England)
BACKGROUND: Previous scoring models such as the Acute Physiologic Assessment and Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA) scoring systems do not adequately predict mortality of patients undergoing co...

Predicting patient outcomes in psychiatric hospitals with routine data: a machine learning approach.

BMC medical informatics and decision making
BACKGROUND: A common problem in machine learning applications is availability of data at the point of decision making. The aim of the present study was to use routine data readily available at admission to predict aspects relevant to the organization...

DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening.

Genomics, proteomics & bioinformatics
Accurate identification of compound-protein interactions (CPIs) in silico may deepen our understanding of the underlying mechanisms of drug action and thus remarkably facilitate drug discovery and development. Conventional similarity- or docking-base...

Prospective and External Evaluation of a Machine Learning Model to Predict In-Hospital Mortality of Adults at Time of Admission.

JAMA network open
IMPORTANCE: The ability to accurately predict in-hospital mortality for patients at the time of admission could improve clinical and operational decision-making and outcomes. Few of the machine learning models that have been developed to predict in-h...

Machine learning for syndromic surveillance using veterinary necropsy reports.

PloS one
The use of natural language data for animal population surveillance represents a valuable opportunity to gather information about potential disease outbreaks, emerging zoonotic diseases, or bioterrorism threats. In this study, we evaluate machine lea...

Virtual genetic diagnosis for familial hypercholesterolemia powered by machine learning.

European journal of preventive cardiology
AIMS: Familial hypercholesterolemia (FH) is the most common genetic disorder of lipid metabolism. The gold standard for FH diagnosis is genetic testing, available, however, only in selected university hospitals. Clinical scores - for example, the Dut...

Multiparametric radiomics methods for breast cancer tissue characterization using radiological imaging.

Breast cancer research and treatment
BACKGROUND AND PURPOSE: Multiparametric radiological imaging is vital for detection, characterization, and diagnosis of many different diseases. Radiomics provide quantitative metrics from radiological imaging that may infer potential biological mean...

Using artificial intelligence (AI) to predict postoperative surgical site infection: A retrospective cohort of 4046 posterior spinal fusions.

Clinical neurology and neurosurgery
OBJECTIVES: Machine Learning and Artificial Intelligence (AI) are rapidly growing in capability and increasingly applied to model outcomes and complications within medicine. In spinal surgery, post-operative surgical site infections (SSIs) are a rare...

Application of a machine learning algorithm to predict malignancy in thyroid cytopathology.

Cancer cytopathology
BACKGROUND: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) comprises 6 categories used for the diagnosis of thyroid fine-needle aspiration biopsy (FNAB). Each category has an associated risk of malignancy, which is important in the ...