AIMC Topic: ROC Curve

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Modest Clostridiodes difficile infection prediction using machine learning models in a tertiary care hospital.

Diagnostic microbiology and infectious disease
Previous studies have shown promising results of machine learning (ML) models for predicting health outcomes. We develop and test ML models for predicting Clostridioides difficile infection (CDI) in hospitalized patients. This is a retrospective coho...

An improved clear cell renal cell carcinoma stage prediction model based on gene sets.

BMC bioinformatics
BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma and accounts for cancer-related deaths. Survival rates are very low when the tumor is discovered in the late-stage. Thus, developing an efficient s...

Prospective Analysis Using a Novel CNN Algorithm to Distinguish Atypical Ductal Hyperplasia From Ductal Carcinoma in Situ in Breast.

Clinical breast cancer
INTRODUCTION: We previously developed a convolutional neural networks (CNN)-based algorithm to distinguish atypical ductal hyperplasia (ADH) from ductal carcinoma in situ (DCIS) using a mammographic dataset. The purpose of this study is to further va...

Matrix factorization with neural network for predicting circRNA-RBP interactions.

BMC bioinformatics
BACKGROUND: Circular RNA (circRNA) has been extensively identified in cells and tissues, and plays crucial roles in human diseases and biological processes. circRNA could act as dynamic scaffolding molecules that modulate protein-protein interactions...

Using machine learning models to predict the initiation of renal replacement therapy among chronic kidney disease patients.

PloS one
Starting renal replacement therapy (RRT) for patients with chronic kidney disease (CKD) at an optimal time, either with hemodialysis or kidney transplantation, is crucial for patient's well-being and for successful management of the condition. In thi...

CRISPRpred(SEQ): a sequence-based method for sgRNA on target activity prediction using traditional machine learning.

BMC bioinformatics
BACKGROUND: The latest works on CRISPR genome editing tools mainly employs deep learning techniques. However, deep learning models lack explainability and they are harder to reproduce. We were motivated to build an accurate genome editing tool using ...