An underlying association between primary open-angle glaucoma (POAG) and COVID-19 has been hypothesized, but the causal link and shared mechanisms remain unclear. This study integrates epidemiological and bioinformatics approaches to investigate thei...
Survivors of severe COVID-19 often suffer from long-term respiratory issues, but the molecular drivers of this damage remain unclear. This study explored the dynamics of inflammatory, fibrotic, and endothelial biomarkers in hospitalized COVID-19 pati...
BACKGROUND: One of the main challenges with COVID-19 has been that although there are known factors associated with a worse prognosis, clinicians have been unable to predict which patients, with similar risk factors, will die or require intensive car...
BACKGROUND: Infectious diseases remain a critical global health challenge, and the integration of standardized ontologies plays a vital role in managing related data. The Infectious Disease Ontology (IDO) and its extensions, such as the Coronavirus I...
BACKGROUND: The COVID-19 pandemic highlighted significant disparities in vaccine distribution, particularly in low- and middle-income countries (LMICs). Artificial intelligence (AI) has emerged as a potential tool to optimize vaccine distribution pla...
BACKGROUND: Preterm birth, defined as birth at <37 weeks of gestation, is the leading cause of neonatal death globally and the second leading cause of infant mortality in the United States. There is mounting evidence that COVID-19 infection during pr...
The frequent global outbreaks of viral infectious diseases have significantly heightened the urgent demand for molecular testing at home. However, the labor-intensive sample preparation and nucleic acid amplification steps, along with the complexity ...
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlights the importance of monitoring immune responses to guide vaccination strategies. Although neutralizing antibodies (NAbs) have garnered increasing ...
Genome sequencing from wastewater enables accurate and cost-effective identification of SARS-CoV-2 variants. However, existing computational pipelines have limitations in detecting emerging variants not yet characterized in humans. Here, we present a...
The COVID-19 pandemic, driven by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has underscored the need to understand the virus's evolution due to its global health impact. This study employed RNA sequencing (RNA-Seq) to analyze g...
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