AIMC Topic: SARS-CoV-2

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Machine learning to understand risks for severe COVID-19 outcomes: a retrospective cohort study of immune-mediated inflammatory diseases, immunomodulatory medications, and comorbidities in a large US health-care system.

The Lancet. Digital health
BACKGROUND: In the context of immune-mediated inflammatory diseases (IMIDs), COVID-19 outcomes are incompletely understood and vary considerably depending on the patient population studied. We aimed to analyse severe COVID-19 outcomes and to investig...

Analysis of Critical Incident Reports Using Natural Language Processing.

Studies in health technology and informatics
UNLABELLED: A Critical Incident Reporting System (CIRS) collects anecdotal reports from employees, which serve as a vital source of information about incidents that could potentially harm patients.

Development of a machine learning model and nomogram to predict seizures in children with COVID-19: a two-center study.

Journal of tropical pediatrics
OBJECTIVE: This study aimed to use machine learning to evaluate the risk factors of seizures and develop a model and nomogram to predict seizures in children with coronavirus disease 2019 (COVID-19).

Genotypic-phenotypic landscape computation based on first principle and deep learning.

Briefings in bioinformatics
The relationship between genotype and fitness is fundamental to evolution, but quantitatively mapping genotypes to fitness has remained challenging. We propose the Phenotypic-Embedding theorem (P-E theorem) that bridges genotype-phenotype through an ...

[Identifying Novel Coronavirus Pneumonia With CT Images: A Deep Learning Approach With Detail Upsampling and Attention Guidance].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
OBJECTIVE: To construct a deep learning-based target detection method to help radiologists perform rapid diagnosis of lesions in the CT images of patients with novel coronavirus pneumonia (NCP) by restoring detailed information and mining local infor...

Protein-protein and protein-nucleic acid binding site prediction via interpretable hierarchical geometric deep learning.

GigaScience
Identification of protein-protein and protein-nucleic acid binding sites provides insights into biological processes related to protein functions and technical guidance for disease diagnosis and drug design. However, accurate predictions by computati...

Does Cohort Selection Affect Machine Learning from Clinical Data?

AMIA ... Annual Symposium proceedings. AMIA Symposium
This study investigates cohort selection and its effects on the quality of machine learning (ML) models trained on clinical data, focusing on measurements taken within the first 48 hours of hospital admission. It discusses the potential repercussions...

Optimizing Medication Querying Using Ontology-Driven Approach with OMOP: with an application to a large-scale COVID-19 EHR dataset.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Efficient querying for medication information in Electronic Health Record (EHR) datasets is crucial for effective patient care and clinical research. To address the complexity and data volume challenges involved in efficient medication information re...

Advanced Lung Disease Detection: CBAM-Augmented, Lightweight EfficientNetB2 with Visual Insights.

Current medical imaging
INTRODUCTION: This paper presents a multichannel deep-learning method for detecting lung diseases using chest X-ray images. Using EfficientNetB0 through EfficientNetB7 pretrained models, the methodology offers improved performance in classifying COVI...

Pneumonia detection on chest X-rays from Xception-based transfer learning and logistic regression.

Technology and health care : official journal of the European Society for Engineering and Medicine
Pneumonia is a dangerous disease that kills millions of children and elderly patients worldwide every year. The detection of pneumonia from a chest x-ray is perpetrated by expert radiologists. The chest x-ray is cheaper and is most often used to diag...