AIMC Topic: Schizophrenia

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A review on neural network models of schizophrenia and autism spectrum disorder.

Neural networks : the official journal of the International Neural Network Society
This survey presents the most relevant neural network models of autism spectrum disorder and schizophrenia, from the first connectionist models to recent deep neural network architectures. We analyzed and compared the most representative symptoms wit...

Decentralized distribution-sampled classification models with application to brain imaging.

Journal of neuroscience methods
BACKGROUND: In this age of big data, certain models require very large data stores in order to be informative and accurate. In many cases however, the data are stored in separate locations requiring data transfer between local sites which can cause v...

Multivariate classification of schizophrenia and its familial risk based on load-dependent attentional control brain functional connectivity.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Patients with schizophrenia (SCZ), as well as their unaffected siblings (SIB), show functional connectivity (FC) alterations during performance of tasks involving attention. As compared with SCZ, these alterations are present in SIB to a lesser exten...

Use of Natural Language Processing to identify Obsessive Compulsive Symptoms in patients with schizophrenia, schizoaffective disorder or bipolar disorder.

Scientific reports
Obsessive and Compulsive Symptoms (OCS) or Obsessive Compulsive Disorder (OCD) in the context of schizophrenia or related disorders are of clinical importance as these are associated with a range of adverse outcomes. Natural Language Processing (NLP)...

Generalizability of machine learning for classification of schizophrenia based on resting-state functional MRI data.

Human brain mapping
Machine learning has increasingly been applied to classification of schizophrenia in neuroimaging research. However, direct replication studies and studies seeking to investigate generalizability are scarce. To address these issues, we assessed withi...

A Multi-Domain Connectome Convolutional Neural Network for Identifying Schizophrenia From EEG Connectivity Patterns.

IEEE journal of biomedical and health informatics
OBJECTIVE: We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently...

Using machine learning to explain the heterogeneity of schizophrenia. Realizing the promise and avoiding the hype.

Schizophrenia research
Despite extensive research and prodigious advances in neuroscience, our comprehension of the nature of schizophrenia remains rudimentary. Our failure to make progress is attributed to the extreme heterogeneity of this condition, enormous complexity o...

Identifying schizophrenia subgroups using clustering and supervised learning.

Schizophrenia research
Schizophrenia has a 1% incidence rate world-wide and those diagnosed present with positive (e.g. hallucinations, delusions), negative (e.g. apathy, asociality), and cognitive symptoms. However, both symptom burden and associated brain alterations are...

Characterizing functional regional homogeneity (ReHo) as a B-SNIP psychosis biomarker using traditional and machine learning approaches.

Schizophrenia research
BACKGROUND: Recently, a biologically-driven psychosis classification (B-SNIP Biotypes) was derived using brain-based cognitive and electrophysiological markers. Here, we characterized a local functional-connectivity measure, regional homogeneity (ReH...