BACKGROUND: With the development of third-generation sequencing (TGS) technologies, people are able to obtain DNA sequences with lengths from 10s to 100s of kb. These long reads allow protein domain annotation without assembly, thus can produce impor...
BACKGROUND: Most studies on synthetic computed tomography (sCT) generation for brain rely on in-house developed methods. They often focus on performance rather than clinical feasibility. Therefore, the aim of this work was to validate sCT images gene...
Automatic polyp detection has been proven to be crucial in improving the diagnosis accuracy and reducing colorectal cancer mortality during the precancerous stage. However, the performance of deep neural networks may degrade severely when being deplo...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
Evidence has accumulated enough to prove non-coding RNAs (ncRNAs) play important roles in cellular biological processes and disease pathogenesis. High throughput techniques have produced a large number of ncRNAs whose function remains unknown. Since ...
The question of molecular similarity is core in cheminformatics and is usually assessed via a comparison based on vectors of properties or molecular fingerprints. We recently exploited variational autoencoders to embed 6M molecules in a chemical spa...
Tissue Biomarkers are information written in the tissue and used in Pathology to recognize specific subsets of patients with diagnostic, prognostic or predictive purposes, thus representing the key elements of Personalized Medicine. The advent of Art...
IEEE transactions on neural networks and learning systems
Apr 2, 2021
The Bayesian method is capable of capturing real-world uncertainties/incompleteness and properly addressing the overfitting issue faced by deep neural networks. In recent years, Bayesian neural networks (BNNs) have drawn tremendous attention to artif...
This paper sketches a new approach using Fuzzy Cognitive Maps (FCMs) to operably map and simulate digital transformation in architecture and urban planning. Today these processes are poorly understood. Many current studies on digital transformation a...
Mice emit ultrasonic vocalizations (USVs) that communicate socially relevant information. To detect and classify these USVs, here we describe VocalMat. VocalMat is a software that uses image-processing and differential geometry approaches to detect U...
The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers using machine learning (ML). However, metagenomics-specific software is scarce, and overoptimistic evaluation and limited cross-study generalization are prevailing i...
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