AIMC Topic:
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Extracting chemical-protein interactions from biomedical literature via granular attention based recurrent neural networks.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: The extraction of interactions between chemicals and proteins from biomedical literature is important for many biomedical tasks such as drug discovery and precision medicine. In the existing systems, the methods achieving co...

Analysis of parameters affecting blood oxygen saturation and modeling of fuzzy logic system for inspired oxygen prediction.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Fraction of Inspired Oxygen is one of the arbitrary set ventilator parameters which has critical influence on the concentration of blood oxygen. Normally mechanical ventilators providing respiratory assistance are tuned manu...

An adverse drug effect mentions extraction method based on weighted online recurrent extreme learning machine.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Automatic extraction of adverse drug effect (ADE) mentions from biomedical texts is a challenging research problem that has attracted significant attention from the pharmacovigilance and biomedical text mining communities. I...

MLSeq: Machine learning interface for RNA-sequencing data.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: In the last decade, RNA-sequencing technology has become method-of-choice and prefered to microarray technology for gene expression based classification and differential expression analysis since it produces less noisy data....

An open access medical knowledge base for community driven diagnostic decision support system development.

BMC medical informatics and decision making
INTRODUCTION: While early diagnostic decision support systems were built around knowledge bases, more recent systems employ machine learning to consume large amounts of health data. We argue curated knowledge bases will remain an important component ...

mACPpred: A Support Vector Machine-Based Meta-Predictor for Identification of Anticancer Peptides.

International journal of molecular sciences
Anticancer peptides (ACPs) are promising therapeutic agents for targeting and killing cancer cells. The accurate prediction of ACPs from given peptide sequences remains as an open problem in the field of immunoinformatics. Recently, machine learning ...

A novel ECG signal compression method using spindle convolutional auto-encoder.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: With rapid development of telehealth system and cloud platform, traditional 12-ECG signals with high resolution generate heavy burdens in data storage and transmission. This problem is increasingly addressed with various EC...

End-to-End Differentiable Learning of Protein Structure.

Cell systems
Predicting protein structure from sequence is a central challenge of biochemistry. Co-evolution methods show promise, but an explicit sequence-to-structure map remains elusive. Advances in deep learning that replace complex, human-designed pipelines ...

Viable and necrotic tumor assessment from whole slide images of osteosarcoma using machine-learning and deep-learning models.

PloS one
Pathological estimation of tumor necrosis after chemotherapy is essential for patients with osteosarcoma. This study reports the first fully automated tool to assess viable and necrotic tumor in osteosarcoma, employing advances in histopathology digi...