AIMC Topic: Synthetic Biology

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TensorFlow: Biology's Gateway to Deep Learning?

Cell systems
TensorFlow is Google's recently released open-source software for deep learning. What are its applications for computational biology?

Artificial intelligence and synthetic biology: A tri-temporal contribution.

Bio Systems
Artificial intelligence can make numerous contributions to synthetic biology. I would like to suggest three that are related to the past, present and future of artificial intelligence. From the past, works in biology and artificial systems by Turing ...

Managing bioengineering complexity with AI techniques.

Bio Systems
Our capabilities for systematic design and engineering of biological systems are rapidly increasing. Effectively engineering such systems, however, requires the synthesis of a rapidly expanding and changing complex body of knowledge, protocols, and m...

The role of regulation in the origin and synthetic modelling of minimal cognition.

Bio Systems
In this paper we address the question of minimal cognition by investigating the origin of some crucial cognitive properties from the very basic organisation of biological systems. More specifically, we propose a theoretical model of how a system can ...

Synthetic Biology for Designing Allostery and Its Potential Biomedical Applications.

Journal of molecular biology
Allosteric regulation of protein function, where a perturbation at one site induces a conformational shift or alters dynamics at a distal functional site, plays a key role in numerous biological processes. The ability to introduce allostery using syn...

[Synthetic promoters: theory, design, and prospects].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Synthetic promoters are novel promoters artificially designed and do not exist in nature. They can initiate the expression of target genes with specific regulatory modes, offering advantages such as high expression efficiency, precise regulation, and...

A Novel Linear Machine Learning Method Based on DNA Hybridization Reaction Circuit.

IEEE transactions on nanobioscience
DNA hybridization reaction is a significant technology in the field of semi-synthetic biology and holds great potential for use in biological computation. In this study, we propose a novel machine learning model based on a DNA hybridization reaction ...

Paving the way for bacteria-based drug delivery: biohybrid microrobots emerging from microrobotics and synthetic biology.

Advanced drug delivery reviews
Advances in microrobotics and synthetic biology are paving the way for innovative solutions to long-standing challenges in drug delivery. Both fields have independently worked on engineering bacteria as a therapeutic system, focusing on enhancing pro...

Designer artificial environments for membrane protein synthesis.

Nature communications
Protein synthesis in natural cells involves intricate interactions between chemical environments, protein-protein interactions, and protein machinery. Replicating such interactions in artificial and cell-free environments can control the precision of...

[Machine learning-aided design of synthetic biological parts and circuits].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Synthetic biology is an emerging interdisciplinary field at the convergence of biology, engineering, and computer science. It employs a bottom-up approach to progressively design biological parts, devices, and circuits, aiming to create artificial bi...