IMPORTANCE: As currently used, microperimetry is a burdensome clinical testing modality for testing retinal sensitivity requiring long testing times and trained technicians.
Obtaining expert labels in clinical imaging is difficult since exhaustive annotation is time-consuming. Furthermore, not all possibly relevant markers may be known and sufficiently well described a priori to even guide annotation. While supervised le...
PURPOSE: To train a deep learning (DL) algorithm that quantifies glaucomatous neuroretinal damage on fundus photographs using the minimum rim width relative to Bruch membrane opening (BMO-MRW) from spectral-domain optical coherence tomography (SDOCT)...
PURPOSE OF THE REVIEW: Rheumatoid arthritis (RA) is a chronic, autoimmune disease which may result in a higher risk of cardiovascular (CV) events and stroke. Tissue characterization and risk stratification of patients with rheumatoid arthritis are a ...
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Jan 4, 2019
PURPOSE: With the aging population and the global diabetes epidemic, the prevalence of age-related macular degeneration (AMD) and diabetic macular edema (DME) diseases which are the leading causes of blindness is further increasing. Intravitreal inje...
Artificial intelligence (AI) based on convolutional neural networks (CNNs) has a great potential to enhance medical workflow and improve health care quality. Of particular interest is practical implementation of such AI-based software as a cloud-base...
Maculopathy is a group of retinal disorders that affect macula and cause severe visual impairment if not treated in time. Many computer-aided diagnostic methods have been proposed over the past that automatically detect macular diseases. However, to ...
Automatic and reliable segmentation for geographic atrophy in spectral-domain optical coherence tomography (SD-OCT) images is a challenging task. To develop an effective segmentation method, a two-stage deep learning framework based on an auto-encode...
PURPOSE: Previous approaches using deep learning (DL) algorithms to classify glaucomatous damage on fundus photographs have been limited by the requirement for human labeling of a reference training set. We propose a new approach using quantitative s...
The benchmark method for the evaluation of breast cancers involves microscopic testing of a hematoxylin and eosin (H&E)-stained tissue biopsy. Resurgery is required in 20% to 30% of cases because of incomplete excision of malignant tissues. Therefore...