AIMC Topic: Virus Diseases

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Circulating microRNAs in viral myocarditis: Advancements in biological understanding and potential clinical applications.

Gene
Viral myocarditis (VMC) is a prevalent inflammatory cardiac condition, characterized by highly variable clinical manifestations that present significant challenges for early diagnosis and the development of personalized treatment strategies. Conseque...

Viral interferon antagonism shapes host tropism.

PLoS pathogens
Outbreaks of zoonotic viruses in human populations highlight the need to understand the molecular factors that influence viral host tropism and interspecies transmission. A virus's host range is determined not only by the expression of host factors t...

Synthetic biology meets diagnostics: Engineering biosensing platforms for rapid and accurate pathogen and viral detection.

Biosensors & bioelectronics
The integration of synthetic biology with biosensor technologies has catalyzed a paradigm shift in the development of programmable, field-deployable diagnostic systems for precision detection of pathogens and viral threats. This review provides a com...

Image-based honey bee larval viral and bacterial diagnosis using machine learning.

Scientific reports
Honey bees are essential pollinators of ecosystems and agriculture worldwide. With an estimated 50-80% of crops pollinated by honey bees, they generate approximately $20 billion annually in market value in the U.S. alone. However, commercial beekeepe...

Respiratory viral infections: when and where? A scoping review of spatiotemporal methods.

Journal of global health
BACKGROUND: Respiratory viral infections pose a substantial disease burden worldwide. Spatiotemporal techniques help identify transmission patterns of these infections, thereby supporting timely control and prevention efforts. We aimed to synthesise ...

A Review of In Silico Approaches for Discovering Natural Viral Protein Inhibitors in Aquaculture Disease Control.

Journal of fish diseases
Viral diseases pose a significant threat to the sustainability of global aquaculture, causing economic losses and compromising food security. Traditional control methods often demonstrate limited effectiveness, highlighting the need for alternative a...

Plasma cell-free RNA signatures of inflammatory syndromes in children.

Proceedings of the National Academy of Sciences of the United States of America
Inflammatory syndromes, including those caused by infection, are a major cause of hospital admissions among children and are often misdiagnosed because of a lack of advanced molecular diagnostic tools. In this study, we explored the utility of circul...

Combination therapy synergism prediction for virus treatment using machine learning models.

PloS one
Combining different drugs synergistically is an essential aspect of developing effective treatments. Although there is a plethora of research on computational prediction for new combination therapies, there is limited to no research on combination th...

Coordinating virus research: The Virus Infectious Disease Ontology.

PloS one
The COVID-19 pandemic prompted immense work on the investigation of the SARS-CoV-2 virus. Rapid, accurate, and consistent interpretation of generated data is thereby of fundamental concern. Ontologies-structured, controlled, vocabularies-are designed...

Leveraging machine learning to distinguish between bacterial and viral induced pharyngitis using hematological markers: a retrospective cohort study.

Scientific reports
Accurate differentiation between bacterial and viral-induced pharyngitis is recognized as essential for personalized treatment and judicious antibiotic use. From a cohort of 693 patients with pharyngitis, data from 197 individuals clearly diagnosed w...