AIMC Topic: Virus Replication
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Paraconsistents artificial neural networks applied to the study of mutational patterns of the F subtype of the viral strains of HIV-1 to antiretroviral therapy.
Anais da Academia Brasileira de Ciencias
Mar 4, 2016
The high variability of HIV-1 as well as the lack of efficient repair mechanisms during the stages of viral replication, contribute to the rapid emergence of HIV-1 strains resistant to antiretroviral drugs. The selective pressure exerted by the drug ...
Use of uniform designs in combination with neural networks for viral infection process development.
Biotechnology progress
Jan 27, 2015
This work aimed to compare the predictive capacity of empirical models, based on the uniform design utilization combined to artificial neural networks with respect to classical factorial designs in bioprocess, using as example the rabies virus replic...
The Spontaneous Control of HIV Replication is Characterized by Decreased Pathological Changes in the Gut-associated Lymphoid Tissue.
Current HIV research
Jan 1, 2018
BACKGROUND: HIV infection induces alterations in the gut-associated lymphoid tissue (GALT) that constitutes the most important site for viral replication due to the extensive presence of effector memory T-cells. In the case of HIV-controllers, severa...
High Mobility Group Box 1 Protein Enhances HIV Replication in Newly Infected Primary T Cells.
Clinical laboratory
Dec 1, 2016
BACKGROUND: High-mobility group box 1 (HMGB1), a DNA-binding protein, has recently been shown to have effects on HIV replication, but the effects are dependent on the cell type and the timing of infection. Using human primary T cells, this study aime...
Interferon-α and inosine pranobex-mediated inhibition of reploication of human RNA viruses in vitro.
Medycyna doswiadczalna i mikrobiologia
Jan 1, 2016
INTRODUCTION: Interferon- a (IFN-a), produced by immune cells, exhibits pleiotropic anti- viral activity. Inosine pranobex (PI), a synthetic derivative of a purine, shows direct anti- viral activity, and also acts indirectly, by activation of immune ...
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