This paper proposes a deep-learning-based image enhancement approach that can generate high-resolution micro-CT-like images from multidetector computed tomography (MDCT). A total of 12,500 MDCT and micro-CT image pairs were obtained from 25 vertebral...
Cochlear implants restore hearing in patients with severe to profound deafness by delivering electrical stimuli inside the cochlea. Understanding stimulus current spread, and how it correlates to patient-dependent factors, is hampered by the poor acc...
Journal of the mechanical behavior of biomedical materials
Sep 15, 2021
3D image-based finite element (FE) and bone volume fraction (BV/TV)/fabric tensor modeling techniques are currently used to determine the apparent stiffness tensor of trabecular bone for assessing its anisotropic elastic behavior. Inspired by the rec...
INTRODUCTION: This study proposes a novel data pipeline based on micro-computed tomographic (micro-CT) data for training the U-Net network to realize the automatic and accurate segmentation of the pulp cavity and tooth on cone-beam computed tomograph...
Journal of the mechanical behavior of biomedical materials
Aug 14, 2021
Machine learning methods have the potential to transform imaging techniques and analysis for healthcare applications with automation, making diagnostics and treatment more accurate and efficient, as well as to provide mechanistic insights into tissue...
We are developing imaging methods for a co-clinical trial investigating synergy between immunotherapy and radiotherapy. We perform longitudinal micro-computed tomography (micro-CT) of mice to detect lung metastasis after treatment. This work explores...
Micro-CT has important applications in biomedical research due to its ability to perform high-precision 3D imaging of micro-architecture in a non-invasive way. Because of the limited power of the radiation source, it is difficult to obtain a high sig...
After an ischemic event, disruptive changes in the healthy myocardium may gradually develop and may ultimately turn into fibrotic scar. While these structural changes have been described by conventional imaging modalities mostly on a macroscopic scal...
Tissue micro-morphological abnormalities and interrelated quantitative data can provide immediate evidences for tumorigenesis and metastasis in microenvironment. However, the multiscale three-dimensional nondestructive pathological visualization, mea...
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