AIMS: Proliferation of arterial smooth muscle cells (SMCs) and their modulation to alternative mesenchymal phenotypes is central to atherosclerotic lesion growth. It has been studied extensively in mouse models, but a detailed analysis of when and wh... read more
Bulletin of environmental contamination and toxicology
Jan 19, 2026
Per- and polyfluoroalkyl substances (PFAS) are environmentally persistent pollutants, posing challenges for effective remediation. This study presented a machine learning (ML) framework to predict the first-order reaction rate constant (k) of PFAS de... read more
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
Jan 19, 2026
BACKGROUND: Sarcopenia, characterized by progressive skeletal muscle loss, is associated with poor outcomes in various diseases. Traditional methods for assessing muscle cross-sectional area using computed tomography (CT) scans are manual, time-consu... read more
BACKGROUND: Radiation dose reduction is essential in paediatric lung computed tomography (CT). Advances in energy-integrating detector CT and deep-learning reconstruction may enable ultra-low-dose imaging comparable to photon-counting CT. OBJECTIVE: ... read more
OBJECTIVE: This study aims to both develop and evaluate a predictive model for ureteral access sheath(UAS)placement success using preoperative CT-based 3D ureteral imaging and machine learning techniques. Specifically, it investigates the impact of u... read more
European journal of clinical pharmacology
Jan 19, 2026
PURPOSE: The primary purpose of this study is to systematically evaluate how accurately artificial intelligence (AI) models can predict optimal warfarin dosing by incorporating both genetic variations-particularly in VKORC1 and CYP2C9-and clinical pa... read more
Tauopathies are characterised by a progressive accumulation of hyperphosphorylated tau. However, early and intermediate stages remain challenging to quantify due to subtle and heterogeneous morphological characteristics. This study evaluates a deep l... read more
The transition from laparoscopic to robotic surgery for left-sided colorectal cancer raises safety concerns during the learning curve, particularly when complex cases are preferentially selected for the robotic platform. We evaluated a machine learni... read more
Journal of molecular neuroscience : MN
Jan 19, 2026
Huntington's disease (HD) is a rare, inherited neurodegenerative disorder caused by the expanded CAG repeats in the huntingtin gene. The HD domain still lacks detailed knowledge of validated drug targets, limiting the effectiveness of classical metho... read more
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