AI Medical Compendium

Barriers and facilitators to implementing the living guideline development framework in oncology: a mixed methods study.

BMJ open Jan 16, 2026

OBJECTIVE: To explore stakeholder experiences with implementing the living guideline (LG) development framework in oncology, and to identify barriers, facilitators and solutions to support its uptake and sustainability. DESIGN: An exploratory sequent... read more

Neoplasms Qualitative Research Cross-Sectional Studies Male Medical Oncology Humans Practice Guidelines as Topic Female Stakeholder Participation Surveys and Questionnaires Interviews as Topic

A scalable computational framework for predicting gene expression from candidate cis-regulatory elements.

Genome research Jan 16, 2026

Deciphering the relationships between cis-regulatory elements (CREs) and target gene expression has been a long-standing unsolved problem in molecular biology, and the dynamics of CREs in different cell types make this problem more challenging. To ad... read more

Artificial intelligence-based fluid quantification predicts clinical outcomes in diabetic macular oedema eyes treated with intravitreal dexamethasone implants: DIADEMA project.

The British journal of ophthalmology Jan 16, 2026

AIM: To explore associations between artificial intelligence (AI)-based baseline optical coherence tomography (OCT) fluid compartment quantifications and 12-month visual outcomes in diabetic macular oedema (DME) eyes treated with the intravitreal dex... read more

Correction in: Artificial Intelligence-Assisted Capsule Endoscopy Versus Conventional Capsule Endoscopy for Detection of Small Bowel Lesions: A Systematic Review and Meta-Analysis.

Journal of gastroenterology and hepatology Jan 16, 2026

Deconstruction by C. thermocellum-from microbe mediated to dynamic redistribution of cellulosomes.

Life science alliance Jan 16, 2026

Clostridium thermocellum is one of the most efficient microorganisms for the deconstruction of cellulosic biomass. To achieve this high level of cellulolytic activity, C. thermocellum uses large multienzyme complexes known as cellulosomes to break do... read more

Cellulosomes Cell Wall Acetivibrio thermocellus Biomass Cellulose

Development and external validation of machine learning approaches for risk prediction of cardiovascular disease in individuals with schizophrenia: a nationwide Swedish and Danish study.

BMJ mental health Jan 16, 2026

BACKGROUND: Currently available cardiovascular disease (CVD) risk prediction tools may underestimate the risk in individuals with schizophrenia. OBJECTIVE: To develop and externally validate 5-year CVD risk prediction models for people with schizophr... read more

Machine Learning Female Humans Adult Male Sweden Aged Risk Assessment Denmark Cardiovascular Diseases Registries Middle Aged Schizophrenia

NLP-ROPCare: predicting retinopathy of prematurity with admission notes using natural language processing.

BMJ open ophthalmology Jan 16, 2026

OBJECTIVES: Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide, requiring more efficient models to help predict treatment-requiring ROP. Our study aimed to develop a new prediction model for ROP occurrence and seve... read more

Retinopathy of Prematurity China Infant, Newborn Natural Language Processing Male Humans Infant, Premature Retrospective Studies Machine Learning Gestational Age Female

Deep learning algorithm for semiquantification of spinal inflammation in axial spondyloarthritis.

RMD open Jan 16, 2026

OBJECTIVE: To develop a deep learning algorithm for semiquantification of spinal inflammation in patients with axial spondyloarthritis (SpA). METHODS: The study included 330 participants with axial SpA. All patients underwent whole spine MRI with sho... read more

Female Adult Male Middle Aged Humans Algorithms Spondylarthritis Axial Spondyloarthritis Magnetic Resonance Imaging Deep Learning Inflammation Spine

Predicting the progression of difficult-to-treat rheumatoid arthritis by a machine learning scoring system, from the FIRST registry.

RMD open Jan 16, 2026

OBJECTIVES: This study aimed to develop and validate a prediction model for the future progression of difficult-to-treat rheumatoid arthritis (D2T RA) and support the precise use of biologic and targeted synthetic disease-modifying antirheumatic drug... read more

Registries Antirheumatic Agents Adult Humans Severity of Illness Index Machine Learning Male Arthritis, Rheumatoid Middle Aged Prognosis Disease Progression Female Aged

Grape expectations: disentangling environmental drivers of microbiome establishment in winegrowing ecosystems.

NPJ biofilms and microbiomes Jan 16, 2026

Microbial communities play a central role in viticulture, influencing wine characteristics (a concept termed microbial terroir). Yet, the individual factors shaping these microbiomes remain poorly understood. We conducted a multi-year, large-scale su... read more

Artificial Intelligence Medical Compendium