Infectious Disease

Hepatitis

Latest AI and machine learning research in hepatitis for healthcare professionals.

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DV-SFT: Direct Vision Supervision for Fine-Grained Visual Understanding

Multimodal large language models are typically trained end-to-end to predict ground-truth answers, y...

Identification of amino acid metabolism-related biomarkers in liver fibrosis: a transcriptomic analysis with experimental validation

Background Liver fibrosis (LF) represents a pivotal pathological phase in the advancement of chronic...

Fusion in Your Way: Aligning Image Fusion with Heterogeneous Demands via Direct Preference Optimization

As a key technique in multi-modal processing, infrared and visible image fusion (IVIF) plays a cruci...

Deep Learning-Based Structure Modeling of the Treponema pallidum Proteome: Insights into Pathogenesis and Syphilis Vaccine Development

Treponema pallidum ssp. pallidum, the causative agent of syphilis, has a small proteome and encompas...

Systems Pharmacology Reveals Type I Interferon and Myeloid-Like B Cell Reprogramming as Druggable Axes in Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) lacks targeted therapies beyond anticoagulation, and its molecular h...

LeapAlign: Post-Training Flow Matching Models at Any Generation Step by Building Two-Step Trajectories

This paper focuses on the alignment of flow matching models with human preferences. A promising way ...

Precision Synthesis of Multi-Tracer PET via VLM-Modulated Rectified Flow for Stratifying Mild Cognitive Impairment

The biological definition of Alzheimer's disease (AD) relies on multi-modal neuroimaging, yet the cl...

Using Synthetic Data for Machine Learning-based Childhood Vaccination Prediction in Narok, Kenya

Background: Limited data utilization in low-resource settings poses a barrier to the vaccine deliver...

ViraHinter: a dual-modal artificial intelligence framework for predicting virus-host interactions

Protein-protein interactions (PPIs) between a virus and its host govern infection, replication, and ...

FixationFormer: Direct Utilization of Expert Gaze Trajectories for Chest X-Ray Classification

Expert eye movements provide a rich, passive source of domain knowledge in radiology, offering a pow...

BAF complexes maintain accessibility at stimulus-responsive chromatin and are required for transcriptional stimulus responses

Background Gene expression changes in response to developmental and environmental cues rely on cis-r...

Cov2Pose: Leveraging Spatial Covariance for Direct Manifold-aware 6-DoF Object Pose Estimation

In this paper, we address the problem of 6-DoF object pose estimation from a single RGB image. Indir...

HViLM: A Foundation Model for Viral Genomics Enables Multi-Task Prediction of Pathogenicity, Transmissibility, and Host Tropism

Motivation: The emergence of novel viral pathogens poses critical threats to global health, yet curr...

Sentiment in Clinical Notes: A Predictor for Length of Stay?

Background: Length of stay (LOS) is a critical metric for hospital operational efficiency. While str...

GDPO-SR: Group Direct Preference Optimization for One-Step Generative Image Super-Resolution

Recently, reinforcement learning (RL) has been employed for improving generative image super-resolut...

Polarized Direct Cross-Attention Message Passing in GNNs for Machinery Fault Diagnosis

The reliability of safety-critical industrial systems hinges on accurate and robust fault diagnosis ...

Deep Learning-based Differentiation of Drug-induced Liver Injury and Autoimmune Hepatitis: A Pathological and Computational Approach

Drug-induced liver injury (DILI) is an acute inflammatory liver disease caused not only by prescript...

Discovery of a phenazine thiol conjugase from sparse data using genome-informed machine learning

Machine learning has enabled powerful biological discoveries using models trained on large datasets....

Predicting how perturbations reshape cellular trajectories with PerturbGen

A major challenge in biology is predicting how cells transition between states over time and how per...

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