Oncology/Hematology

Other Cancers

Latest AI and machine learning research in other cancers for healthcare professionals.

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BoneCoT: multicentre validation of a whole-body skeleton foundation model for bone metastases guided by clinician-derived chain of thought.

Given the rising incidence of bone metastases, computed tomography is widely used worldwide as the initial imaging modality for their detection. Accurate diagnosis of bone metastases demands comprehensive evaluation, yet divergent interpretations among specialists can result in diagnostic discrepancies. In clinical practice, precision diagnosis of bone metastases necessitates multidisciplinary col...

Jul 2 2026 42393341

Key molecular mechanisms of mitochondrial metabolic pathways in specific cell subpopulations of pancreatic cancer based on scRNA-seq and bulk RNA-seq.

BACKGROUND: Pancreatic cancer (PC) is a highly malignant tumor with increasing incidence, mortality, and a low five-year survival rate. Mitochondrial metabolic reprogramming plays a crucial role in tumor development, but the molecular mechanisms in different cell subpopulations of PC remain unclear. This study aims to integrate single-cell RNA sequencing (scRNA-seq) and bulk RNA-seq to explore mit...

Jul 2 2026 42391245
Dihydroberberine regulates the ferroptosis-autophagy positive feedback loop in colorectal cancer by targeting PANX2.

BACKGROUND: Colorectal cancer (CRC) is one of the most common malignancies worldwide and remains a major clinical challenge, underscoring the urgent n...

Jul 1 2026 42401068
Explicit Inclusion of Diabetes Mellitus Without Retinopathy Within Diabetic Retinopathy Prediction.

PURPOSE: The purpose of this study was to evaluate whether explicitly modeling diabetes mellitus (DM) without diabetic retinopathy (DR) as its own sta...

Jul 1 2026 42390159
Integrative multi-omics and machine learning reveal PLAUR as a Pan-Cancer prognostic biomarker and potential therapeutic target.

Tumor heterogeneity remains a major barrier to effective cancer therapy, driving the need for novel biomarkers and targeted strategies. A bibliometric...

Jul 1 2026 42391812
SAP18 drives vasculogenic mimicry in esophageal squamous cell carcinoma: a machine learning and multi-omics investigation.

Vasculogenic mimicry (VM), a novel endothelial-independent blood perfusion pathway, is linked to advanced stage and poor prognosis in esophageal squam...

Jul 1 2026 42393238
Fair by chance? On the use of algorithms in therapeutic decisions.

Predictive tools made possible by advances in machine learning techniques may help clinicians make more accurate decisions about who should be allocat...

Jul 1 2026 40316444
MRI for Prostate Cancer Local Staging: AJR Expert Panel Narrative Review.

The incremental value of multiparametric MRI (mpMRI) in prostate cancer staging has been increasingly recognized, with the accumulated literature indi...

Jul 1 2026 41370657
ADC Target Profiling in NSCLC: Generalizable AI Separates TROP-2 and cMET Phenotypes.

PURPOSE: Antibody-drug conjugates (ADC) targeting trophoblast cell surface antigen 2 (TROP-2) and cMET are entering clinical trials in non-small cell ...

Jul 1 2026 41945491
AI-Powered Deep Visual Proteomics Reveals Critical Molecular Transitions in Pancreatic Cancer Precursors.

UNLABELLED: Pancreatic ductal adenocarcinoma (PDAC) evolves through precursors, yet the protein programs governing early progression remain poorly def...

Jul 1 2026 42013410
The Promise of Machine Learning-Based Population Screening for Hepatocellular Carcinoma.

Clusmann and colleagues developed PRE-Screen-HCC, an interpretable machine learning framework that leverages multimodal clinical data from 2 populatio...

Jul 1 2026 42381462
Early prediction of joint space narrowing in rheumatoid arthritis using AI-quantified bilateral joint space asymmetry on hand radiography.

PURPOSE: Joint space narrowing (JSN) in rheumatoid arthritis (RA) can progress even during clinical remission. Conventional imaging lacks sensitivity ...

Jul 1 2026 42384333
A salivary protein panel for detecting malignant transformation of oral leukoplakia.

Oral leukoplakia (OLK) is the most common oral potentially malignant disorder and carries a lifetime risk of transformation to oral squamous cell carc...

Jul 1 2026 42385552
A Systematic Evaluation of Image Preprocessing in Deep Learning Detection and Segmentation of Intracranial Metastatic Disease.

BACKGROUND AND PURPOSE: Image preprocessing is an essential, though often overlooked, part of machine learning, and it is unclear how preprocessing te...

Jul 1 2026 42386367
Machine learning-assisted identification and validation of NRP1 inhibitors through molecular docking and dynamics simulations.

Neuropilin-1 (NRP1) is a key mediator of tumor metastasis and progression by controlling cancer cell migration, angiogenesis, and tumor immune respons...

Jul 1 2026 42386828
Application of a deep learning method based on CBCT panoramic reconstruction images for differentiating operationally defined cystic and neoplastic jaw lesions from osteomyelitis: a single-center retrospective study.

This single-center retrospective study developed and internally validated a two-dimensional deep learning model based on cone-beam computed tomography...

Jul 1 2026 42386861
BEAMSTER: Brain mEtAstases segMentation for STEreotactic Radiotherapy, A Retrospective MRI Dataset with Expert Segmentations.

We present a retrospective dataset of contrast-enhanced T1-weighted magnetic resonance imaging scans from 140 patients with brain metastases who under...

Jul 1 2026 42387017
A novel cross-attentive network for classifying cervical metastatic lymph nodes on B- and D-mode ultrasound images in oral squamous cell carcinoma.

OBJECTIVES: This study proposes a deep convolutional neural network model that integrates B-mode and D-mode ultrasound images to classify metastatic l...

Jul 1 2026 41208043
Integrated analysis of single-cell and bulk-RNA sequencing data reveals drug therapeutic targets and prognostic biomarkers related to ribosome biogenesis in hepatocellular carcinoma.

BACKGROUND: Ribosome biogenesis is involved in the progression of hepatocellular carcinoma (HCC), but the specific mechanisms and diagnostic values of...

Jul 1 2026 42170964
A Survey of Automatic Sleep Staging: Technical Route, Technical Challenges, and Future Perspectives.

A complete human sleep consists of multiple states, each of which has its own unique and typical characteristics. A clear definition of these states l...

Jul 1 2026 42253214
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