Latest AI and machine learning research in rheumatology for healthcare professionals.
Higenamine (HM) is a naturally occurring benzylisoquinoline alkaloid found in plants and is classified as an S3 prohibited substance in the 2020 World Anti-Doping Agency report. To prevent doping violations in competitive sports, it is essential to develop timely and accurate detection methods. In this study, we propose, for the first time, a detection method that combines artificial intelligence ...
UNLABELLED: Glioblastomas are incurable primary brain tumors that depend on neural-like cellular processes, tumor microtubes (TM), to invade the brain. TMs also interconnect single tumor cells to a communicating multicellular network that resists current therapies. In this study, we developed a combined, comprehensive in vitro/in vivo anti-TM drug screening approach, including machine learning-bas...
Gout, a prevalent and treatable form of crystal-induced arthritis, results from monosodium urate (MSU) crystal deposition in articular and periarticul...
ConspectusViral proteases are essential enzymes required for viral replication and assembly, making them prime antiviral drug targets. However, under ...
PURPOSE: Diabetic macular edema (DME) is a leading cause of vision loss in patients with diabetes. In developed countries, intravitreal (IVT) anti-vas...
Polycystic ovary syndrome (PCOS) represents the leading endocrine problem affecting women of reproductive age, leading to serious complications relate...
Piperine is a common anti-ischemic compound and an active ingredient of herbal medicine for various ailments. It is widely sourced and affordable. How...
MOTIVATION: N6-methyladenine (6 mA) is an important epigenetic modification of DNA that regulates biological processes such as gene expression, transc...
The integrity of competitive athletics is increasingly compromised by sophisticated pharmacologies, rendering traditional sporadic testing of urine an...
Fatigue is a common clinical symptom, and its complex pathophysiological mechanisms markedly affect the quality of life and social function of patient...
Optical neural networks (ONNs) are emerging as a promising neuromorphic computing paradigm for object recognition, offering unprecedented advantages i...
Articular cartilage is crucial for joint function; however, it has limited regenerative capacity when damaged, a hallmark of many rheumatic diseases. ...
Inclusion of physiologically relevant clearance mechanisms into organ-on-a-chip models is essential to reproduce tissue exposure and predict therapeut...
BACKGROUND: Idiopathic membranous nephropathy (IMN) is a major cause of nephrotic syndrome and end-stage renal disease, but the gold-standard diagnost...
PURPOSE: This study aimed to investigate the potential link between age-related macular degeneration (AMD) and systemic lupus erythematosus (SLE), exp...
Neuropsychiatric systemic lupus erythematosus (NPSLE) remains challenging to diagnose because of heterogeneous clinical presentations, nonspecific fin...
Systemic sclerosis (SSc) is a heterogeneous autoimmune disease characterized by fibrosis, vascular damage, and immune dysregulation. In this study, we...
Psoriasis is a skin disorder which mainly occurs as a rash, scaly areas and an itchy skin. The symptoms usually occur on the chest, elbows, and the sc...
The clinical diagnosis of fibromyalgia (FM), a syndrome characterized by generalized pain, is challenging due to its unknown etiology and frequent com...