Rheumatology

Latest AI and machine learning research in rheumatology for healthcare professionals.

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Showing 281-300 of 6,049 articles

Multi-dimensional CT feature screening, construction, and validation of a clinical diagnostic model for thyroid eye disease.

OBJECTIVE: Thyroid eye disease (TED) is an autoimmune condition associated with thyroid dysfunction, often presenting with complex and variable orbital manifestations that pose challenges for early and objective diagnosis. Current diagnostic reliance on clinical assessment and conventional imaging may lack sensitivity or standardization, highlighting an unmet need for quantitative and reproducible...

Mar 26 2026 41895192

Evaluation of large language models in supporting autoimmune liver disease diagnosis and clinical decision-making: advantages of reasoning-based models.

INTRODUCTION: Large-language models (LLMs) have demonstrated increasing potential in healthcare, including applications in clinical information retrieval, medical reasoning, and decision support. Autoimmune liver diseases (AILDs), including autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, and IgG4-related liver disease, are rare and heterogeneous conditions that o...

Mar 25 2026 41879927
Human microphysiological systems of aging recreate the in vivo process expediting evaluation of anti-geronic strategies.

The search for biological mechanisms of human aging is stalled by a lack of suitable models, and it remains unknown whether and to what degree rejuven...

Mar 25 2026 41882175
Anti-Disturbance Proximal Neural Networks for Composite Resource Allocation.

Composite resource allocation problems with general constraints are studied in this article, which frequently arise in networked systems such as smart...

Mar 25 2026 41880243
AI-generated Feedback Following Social Robotic Virtual Patient Interactions and Medical Student Performance: Nonrandomized Quasi-Experimental Study.

BACKGROUND: Virtual patients (VPs) demonstrate effectiveness in improving clinical reasoning skills; however, traditional VP platforms often lack indi...

Mar 25 2026 41881044
Identification of Novel Non-coding Genetic Variants of Serum Urate Using Whole Genome Sequencing in 7,339 Chinese.

OBJECTIVE: To investigate the genetic architecture of low-frequency and rare variants of serum urate (SU) in East Asian populations, aiming to clarify...

Mar 24 2026 41873804
Artificial Intelligence in hepatology: A position paper by the Italian Association for the Study of the Liver.

Artificial Intelligence (AI) is transforming medicine, providing unprecedented opportunities to enhance diagnosis, prognosis, and treatment across all...

Mar 23 2026 41876274
Teriparatide reduces spinal neuroinflammatory phenotypes in ovariectomized rats revealed by an artificial intelligence-driven glial cell morphometry of bright-field tissue sections.

Osteoporosis frequently presents with lower back pain, often accompanied by hypersensitivity, even in the absence of vertebral fractures, suggesting t...

Mar 21 2026 41863388
A decoction-inspired genetic algorithm and PPO reinforcement learning for intelligent molecular discovery: Anti-colorectal cancer candidates from the tiao-pi AnChang formula.

BACKGROUND: Colorectal cancer (CRC) remains among the leading causes of cancer-related mortality worldwide. The TiaoPi AnChang Decoction (TPACD), a tr...

Mar 20 2026 41864092
Exploring exosome-related genes as candidate biomarkers in primary immune thrombocytopenia through transcriptomics and preliminary experimental validation.

Primary Immune Thrombocytopenia (ITP) is an autoimmune disease characterized by thrombocytopenia and bleeding tendency. Exosomes mediate abnormal cros...

Mar 20 2026 41862615
[Large language models in rheumatology : New ways of knowledge transfer].

Medical knowledge is growing exponentially in rheumatology, posing increasing challenges for knowledge dissemination among physicians, educators and p...

Mar 20 2026 41860629
HealthData@MAD-R&I: Protocol for Design and Development of a Regional Health Data Infrastructure to Enable Secondary Use of Health Data in Research and Innovation.

BACKGROUND: The exponential growth of electronic health records (EHRs), together with the recent entry into force of the European Health Data Space (E...

Mar 20 2026 41861842
Integrating bioinformatics, machine learning and molecular biology to elucidate the anti-allergic mechanisms of ginkgo biloba leaves.

Allergic diseases, encompassing allergic asthma, atopic dermatitis, food allergies, have emerged as substantial global public health challenges, with ...

Mar 19 2026 41875747
AI-driven design of antimicrobial peptide for combating resistance and infectious diseases.

The growing threat of antimicrobial resistance, coupled with the challenges of developing new antibiotics, demands innovative therapeutic solutions. A...

Mar 19 2026 41880932
Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic Implications.

INTRODUCTION: Alopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss due to immune dysregulation. Despite advances, it...

Mar 19 2026 41854972
A Scoping Review of Machine Learning Applications for Diagnosis, Classification, and Prognosis in Lupus Nephritis.

BACKGROUND: Over the past decade, machine learning (ML) has transformed histopathology, yet its application in lupus nephritis (LN) remains underexplo...

Mar 18 2026 41848794
Task-adaptive sparse graph structure learning with error-edge pruning and anti-smoothing mechanism.

Graph Structure Learning (GSL) optimizes graph topologies to enhance node representations. This study reveals a critical limitation: while GSL excels ...

Mar 17 2026 41875657
Detection of sample swapping in anti-doping investigations using machine learning.

The substitution of a urine sample that may result in an adverse analytical finding with a previously collected, clean sample is strictly prohibited u...

Mar 17 2026 41844716
Immune checkpoint molecules beyond PD-1 and CTLA-4: emerging targets in autoimmune diseases and cancer immunotherapy.

BACKGROUND: Immune checkpoint molecules are pivotal regulators of immune activation and tolerance, playing critical roles in cancer, autoimmunity, inf...

Mar 17 2026 41842954
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