AI Medical Compendium Journal:
Alzheimer's & dementia : the journal of the Alzheimer's Association

Showing 31 to 38 of 38 articles

Early detection of Alzheimer's disease using deep learning methods.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: Alzheimer's disease (AD), a leading cause of dementia, requires early detection for effective intervention. This study employs AI to analyze multimodal datasets, including clinical, biomarker, and neuroimaging data, using hybrid deep le...

Dual-stream algorithms for dementia detection: Harnessing structured and unstructured electronic health record data, a novel approach to prevalence estimation.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: Identifying individuals with dementia is crucial for prevalence estimation and service planning, but reliable, scalable methods are lacking. We developed novel set algorithms using both structured and unstructured electronic health reco...

Predicting amyloid beta accumulation in cognitively unimpaired older adults: Cognitive assessments provide no additional utility beyond demographic and genetic factors.

Alzheimer's & dementia : the journal of the Alzheimer's Association
BACKGROUND: Integrating non-invasive measures to estimate abnormal amyloid beta accumulation (Aβ+) is key to developing a screening tool for preclinical Alzheimer's disease (AD). The predictive capability of standard neuropsychological tests in estim...

A deep-learning retinal aging biomarker for cognitive decline and incident dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: The utility of retinal photography-derived aging biomarkers for predicting cognitive decline remains under-explored.

Developing and validating a prediction tool for cerebral amyloid angiopathy neuropathological severity.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: Cerebral amyloid angiopathy (CAA) is a cerebrovascular condition, the severity of which can only be determined post mortem. Here, we developed machine learning models, the Florey CAA Score (FCAAS), to predict CAA severity (none/mild/mod...

Machine learning prediction of tau-PET in Alzheimer's disease using plasma, MRI, and clinical data.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: Tau positron emission tomography (PET) is a reliable neuroimaging technique for assessing regional load of tau pathology in the brain, but its routine clinical use is limited by cost and accessibility barriers.

Towards emotionally aligned social robots for dementia: perspectives of care partners and persons with dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association
BACKGROUND: Persons living with dementia and their care partners place a high value on aging in place and maintaining independence. Socially assistive robots - embodied characters or pets that provide companionship and aid through social interaction ...