Journal of the American Medical Informatics Association : JAMIA
May 7, 2025
BACKGROUND: Automated data extraction from echocardiography reports could facilitate large-scale registry creation and clinical surveillance of valvular heart diseases (VHD). We evaluated the performance of open-source large language models (LLMs) gu...
Journal of the American Medical Informatics Association : JAMIA
May 7, 2025
OBJECTIVE: Common Data Elements (CDEs) standardize data collection and sharing across studies, enhancing data interoperability and improving research reproducibility. However, implementing CDEs presents challenges due to the broad range and variety o...
Journal of the American Medical Informatics Association : JAMIA
May 5, 2025
IMPORTANCE: The US healthcare system faces significant challenges, including clinician burnout, operational inefficiencies, and concerns about patient safety. Artificial intelligence (AI), particularly generative AI, has the potential to address thes...
Journal of the American Medical Informatics Association : JAMIA
Aug 7, 2016
OBJECTIVE: Phenotyping algorithms applied to electronic health record (EHR) data enable investigators to identify large cohorts for clinical and genomic research. Algorithm development is often iterative, depends on fallible investigator intuition, a...
Journal of the American Medical Informatics Association : JAMIA
Jun 6, 2016
Inductive machine learning, and in particular extraction of association rules from data, has been successfully used in multiple application domains, such as market basket analysis, disease prognosis, fraud detection, and protein sequencing. The appea...
Journal of the American Medical Informatics Association : JAMIA
May 17, 2016
OBJECTIVE: Our objective is to test the limits of the assumption that better learning from data in medicine requires more granular data. We hypothesize that clinical trial metadata contains latent scientific, clinical, and regulatory expert knowledge...
Journal of the American Medical Informatics Association : JAMIA
May 12, 2016
OBJECTIVE: Traditionally, patient groups with a phenotype are selected through rule-based definitions whose creation and validation are time-consuming. Machine learning approaches to electronic phenotyping are limited by the paucity of labeled traini...
Journal of the American Medical Informatics Association : JAMIA
Apr 27, 2016
OBJECTIVE: Identifying disease-mutation relationships is a significant challenge in the advancement of precision medicine. The aim of this work is to design a tool that automates the extraction of disease-related mutations from biomedical text to adv...
Journal of the American Medical Informatics Association : JAMIA
Apr 27, 2016
OBJECTIVE: (1) To develop an automated algorithm to predict a patient's response (ie, if the patient agrees or declines) before he/she is approached for a clinical trial invitation; (2) to assess the algorithm performance and the predictors on real-w...
Journal of the American Medical Informatics Association : JAMIA
Apr 23, 2016
BACKGROUND: Electronic medical records (EMRs) hold a tremendous amount of information about patients that is relevant to determining the optimal approach to patient care. As medicine becomes increasingly precise, a patient's electronic medical record...