AIMC Topic: A549 Cells

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Kinetics Extraction Modelling and Antiproliferative Activity of Water Extract.

TheScientificWorldJournal Dec 26, 2016
is widely grown in tropical Asia and locally known "belalai gajah" or Sabah snake grass. It has been used as a natural product to treat skin rashes, snake bites, lesion caused by herpes, diabetes, fever, and cancer. Therefore, the objectives of this...
A549 Cells Kinetics Acanthaceae Plant Extracts Antineoplastic Agents, Phytogenic Flavonoids Humans Water
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Graphene oxide as a nanocarrier for controlled release and targeted delivery of an anticancer active agent, chlorogenic acid.

Materials science & engineering. C, Materials for biological applications Dec 5, 2016
We have synthesized graphene oxide using improved Hummer's method in order to explore the potential use of the resulting graphene oxide as a nanocarrier for an active anticancer agent, chlorogenic acid (CA). The synthesized graphene oxide and chlorog...
Delayed-Action Preparations Hydrogen Bonding Microscopy, Electron, Transmission Thermogravimetry Graphite Chlorogenic Acid X-Ray Diffraction Nanocomposites Drug Liberation HeLa Cells Spectrum Analysis, Raman Spectroscopy, Fourier Transform Infrared Hep G2 Cells Oxides Hydrogen-Ion Concentration Humans Cell Survival Antineoplastic Agents A549 Cells
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Cytotoxicity and molecular docking analysis of racemolactone I, a new sesquiterpene lactone isolated from .

Pharmaceutical biology Dec 1, 2021
CONTEXT: Traditionally, Hook. f. (Asteraceae) has been reported to be effective in cancer treatment which motivated the authors to explore the plant for novel anticancer compounds.
Sesquiterpenes A549 Cells HeLa Cells Humans Apoptosis Inula Plant Roots Molecular Docking Simulation Cell Survival Lactones Membrane Potential, Mitochondrial Cell Line, Tumor Antineoplastic Agents, Phytogenic
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Locating transcription factor binding sites by fully convolutional neural network.

Briefings in bioinformatics Sep 2, 2021
Transcription factors (TFs) play an important role in regulating gene expression, thus identification of the regions bound by them has become a fundamental step for molecular and cellular biology. In recent years, an increasing number of deep learnin...
Humans Amino Acid Motifs Neural Networks, Computer Transcription Factors Sequence Analysis, Protein Sequence Analysis, DNA Response Elements MCF-7 Cells Chromatin Immunoprecipitation Sequencing A549 Cells
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Identification of novel CDK2 inhibitors by a multistage virtual screening method based on SVM, pharmacophore and docking model.

Journal of enzyme inhibition and medicinal chemistry Dec 1, 2020
Cyclin-dependent kinase 2 (CDK2) is the family of Ser/Thr protein kinases that has emerged as a highly selective with low toxic cancer therapy target. A multistage virtual screening method combined by SVM, protein-ligand interaction fingerprints (PLI...
HCT116 Cells Support Vector Machine Protein Kinase Inhibitors Molecular Docking Simulation Humans Molecular Structure Dose-Response Relationship, Drug Cyclin-Dependent Kinase 2 Antineoplastic Agents Drug Screening Assays, Antitumor Structure-Activity Relationship Drug Evaluation, Preclinical Cell Proliferation A549 Cells
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A new method using machine learning for automated image analysis applied to chip-based digital assays.

The Analyst May 13, 2019
Chip-based digital assays such as the digital polymerase chain reaction (digital PCR), digital loop-mediated amplification (digital LAMP), digital enzyme-linked immunosorbent assay (digital ELISA) and digital proximity ligation assay (digital PLA) ne...
ROC Curve Single-Cell Analysis Image Processing, Computer-Assisted A549 Cells Humans Machine Learning Fluorescence Optical Imaging Microfluidic Analytical Techniques
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[Effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells and the underlying mechanisms].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences Nov 28, 2018
To investigate the effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells.
 Methods: First, A549 cells were divided into a control group and a low, medium or high dose of Brucea javan...
Humans A549 Cells Lung Neoplasms Carcinoma, Non-Small-Cell Lung Cell Proliferation Autophagy Cell Movement Brucea Plant Oils
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Potential Anticancer Activity of the Parasol Mushroom, Macrolepiota procera (Agaricomycetes), against the A549 Human Lung Cancer Cell Line.

International journal of medicinal mushrooms Jan 1, 2018
Mushrooms comprise an unlimited source of active compounds that have beneficial health effects without known negative side effects and can potentially be used as important therapeutic products against cancer, which is the leading cause of death world...
Cell Movement Apoptosis Neoplasm Invasiveness Humans Antineoplastic Agents Basidiomycota Cell Survival A549 Cells Agaricales
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[Sodium Ferulate Attenuates Oxidative Stressvia Suppressing NALP3 Inflammasome and ERK Signal Pathway].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition Sep 1, 2016
OBJECTIVES: Study the gene and protein expression of NACHT-PYD-containing protein 3 (NALP3) inflammasome and extracellular regulated protein kinase (ERK), the intervention effects of sodium ferulate (SF) in human lung epithelial cells A549 under oxid...
Coumaric Acids NLR Family, Pyrin Domain-Containing 3 Protein Inflammasomes MAP Kinase Signaling System Humans Hydrogen Peroxide Oxidative Stress Flavonoids A549 Cells Interleukin-1beta
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